MK-886


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192 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 arachidonate 5-lipoxygenase LOX5_HUMAN ALOX5 Homo sapiens 240 1110 63
2 peroxisome proliferator activated receptor alpha PPARA_HUMAN PPARA Homo sapiens 5465 1347 38
3 arachidonate 5-lipoxygenase LOX5_RAT Alox5 Rattus norvegicus 25290 439 26
4 arachidonate 5-lipoxygenase activating protein AL5AP_HUMAN ALOX5AP Homo sapiens 241 220 25
5 peroxisome proliferator activated receptor alpha PPARA_MOUSE Ppara Mus musculus 19013 1052 24
6 peroxisome proliferator activated receptor alpha PPARA_RAT Ppara Rattus norvegicus 25747 748 22
7 arachidonate 5-lipoxygenase LOX5_MOUSE Alox5 Mus musculus 11689 283 11
8 arachidonate 5-lipoxygenase activating protein AL5AP_MOUSE Alox5ap Mus musculus 11690 24 10
9 prostaglandin E synthase PTGES_MOUSE Ptges Mus musculus 64292 448 9
10 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 8
11 lysyl oxidase LYOX_HUMAN LOX Homo sapiens 4015 567 8
12 leukotriene C4 synthase LTC4S_HUMAN LTC4S Homo sapiens 4056 117 7
13 arachidonate 5-lipoxygenase activating protein AL5AP_RAT Alox5ap Rattus norvegicus 29624 67 7
14 apolipoprotein A1 APOA1_HUMAN APOA1 Homo sapiens 335 1112 6
15 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
16 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 5
17 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 5
18 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 4
19 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 4
20 PCNA clamp associated factor PAF15_RAT Pclaf Rattus norvegicus 300795 777 4
21 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
22 prostaglandin E synthase PTGES_HUMAN PTGES Homo sapiens 9536 148 3
23 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
24 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 3
25 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 3
26 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 3
27 low density lipoprotein receptor LDLR_MOUSE Ldlr Mus musculus 16835 605 3
28 BCL2-like 1 B2CL1_MOUSE Bcl2l1 Mus musculus 12048 377 3
29 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 3
30 leukotriene C4 synthase LTC4S_MOUSE Ltc4s Mus musculus 17001 32 3
31 polyunsaturated fatty acid lipoxygenase ALOX15 LOX15_RABIT ALOX15 Oryctolagus cuniculus 100009114 211 3
32 patchy fur - Paf Mus musculus 109585 318 3
33 leukotriene B4 receptor 1 LT4R1_MOUSE Ltb4r1 Mus musculus 16995 72 2
34 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 2
35 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 2
36 intercellular adhesion molecule 1 ICAM1_HUMAN ICAM1 Homo sapiens 3383 1840 2
37 peroxisome proliferator-activated receptor gamma PPARG_RAT Pparg Rattus norvegicus 25664 909 2
38 interleukin 17A IL17_MOUSE Il17a Mus musculus 16171 1009 2
39 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 2
40 interleukin 5 IL5_HUMAN IL5 Homo sapiens 3567 698 2
41 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 2
42 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 2
43 glutamate receptor, ionotropic, AMPA1 (alpha 1) GRIA1_MOUSE Gria1 Mus musculus 14799 252 2
44 interleukin 3 IL3_MOUSE Il3 Mus musculus 16187 413 2
45 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 2
46 transient receptor potential cation channel subfamily M member 7 TRPM7_HUMAN TRPM7 Homo sapiens 54822 161 2
47 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2
48 PCNA clamp associated factor PAF15_HUMAN PCLAF Homo sapiens 9768 1129 2
49 immunoglobulin heavy constant epsilon - IGHE Homo sapiens 3497 1005 2
50 ATP binding cassette subfamily C member 1 MRP1_HUMAN ABCC1 Homo sapiens 4363 1125 2