MK-886


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192 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 arachidonate 5-lipoxygenase LOX5_HUMAN ALOX5 Homo sapiens 240 1110 63
2 peroxisome proliferator activated receptor alpha PPARA_HUMAN PPARA Homo sapiens 5465 1347 38
3 arachidonate 5-lipoxygenase LOX5_RAT Alox5 Rattus norvegicus 25290 439 26
4 arachidonate 5-lipoxygenase activating protein AL5AP_HUMAN ALOX5AP Homo sapiens 241 220 25
5 peroxisome proliferator activated receptor alpha PPARA_MOUSE Ppara Mus musculus 19013 1052 24
6 peroxisome proliferator activated receptor alpha PPARA_RAT Ppara Rattus norvegicus 25747 748 22
7 arachidonate 5-lipoxygenase LOX5_MOUSE Alox5 Mus musculus 11689 283 11
8 arachidonate 5-lipoxygenase activating protein AL5AP_MOUSE Alox5ap Mus musculus 11690 24 10
9 prostaglandin E synthase PTGES_MOUSE Ptges Mus musculus 64292 448 9
10 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 8
11 lysyl oxidase LYOX_HUMAN LOX Homo sapiens 4015 567 8
12 leukotriene C4 synthase LTC4S_HUMAN LTC4S Homo sapiens 4056 117 7
13 arachidonate 5-lipoxygenase activating protein AL5AP_RAT Alox5ap Rattus norvegicus 29624 67 7
14 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
15 apolipoprotein A1 APOA1_HUMAN APOA1 Homo sapiens 335 1112 6
16 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 5
17 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 5
18 PCNA clamp associated factor PAF15_RAT Pclaf Rattus norvegicus 300795 777 4
19 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
20 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 4
21 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 4
22 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 3
23 polyunsaturated fatty acid lipoxygenase ALOX15 LOX15_RABIT ALOX15 Oryctolagus cuniculus 100009114 211 3
24 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 3
25 leukotriene C4 synthase LTC4S_MOUSE Ltc4s Mus musculus 17001 32 3
26 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 3
27 BCL2-like 1 B2CL1_MOUSE Bcl2l1 Mus musculus 12048 377 3
28 prostaglandin E synthase PTGES_HUMAN PTGES Homo sapiens 9536 148 3
29 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
30 low density lipoprotein receptor LDLR_MOUSE Ldlr Mus musculus 16835 605 3
31 patchy fur - Paf Mus musculus 109585 318 3
32 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 3
33 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 2
34 lysyl oxidase LYOX_MOUSE Lox Mus musculus 16948 170 2
35 PCNA clamp associated factor PAF15_HUMAN PCLAF Homo sapiens 9768 1129 2
36 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 2
37 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 2
38 immunoglobulin heavy constant epsilon - IGHE Homo sapiens 3497 1005 2
39 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 2
40 fatty acid synthase FAS_HUMAN FASN Homo sapiens 2194 599 2
41 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 2
42 leukotriene B4 receptor 1 LT4R1_MOUSE Ltb4r1 Mus musculus 16995 72 2
43 transient receptor potential cation channel subfamily M member 7 TRPM7_HUMAN TRPM7 Homo sapiens 54822 161 2
44 lactoperoxidase PERL_HUMAN LPO Homo sapiens 4025 472 2
45 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 2
46 peroxisome proliferator-activated receptor gamma PPARG_RAT Pparg Rattus norvegicus 25664 909 2
47 interleukin 17A IL17_MOUSE Il17a Mus musculus 16171 1009 2
48 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 2
49 glutamate receptor, ionotropic, AMPA1 (alpha 1) GRIA1_MOUSE Gria1 Mus musculus 14799 252 2
50 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2