| Protein Name | peroxisome proliferator activated receptor alpha |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25747 |
| Gene Symbol | Ppara |
| UniProt | P37230 (PPARA_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
748
Total Number of Articles : 1276 |
Description |
peroxisome proliferator activated receptor alpha |
| Gene Summary |
Enables several functions, including MDM2/MDM4 family protein binding activity; NFAT protein binding activity; and nuclear receptor activity. Involved in several processes, including behavioral response to nicotine; negative regulation of cell growth involved in cardiac muscle cell development; and response to ethanol. Located in nucleus. Used to study hepatocellular carcinoma; hypertension; hypertensive encephalopathy; and periodontitis. Biomarker of alcoholic hepatitis; fatty liver disease; hydrocephalus; and hypertension. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022] |
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