| Protein Name | arachidonate 5-lipoxygenase activating protein |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11690 |
| Gene Symbol | Alox5ap |
| UniProt | P30355 (AL5AP_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 35 |
Description |
arachidonate 5-lipoxygenase activating protein |
| Gene Summary |
Predicted to enable several functions, including arachidonate binding activity; glutathione peroxidase activity; and glutathione transferase activity. Predicted to contribute to arachidonate 5-lipoxygenase activity. Acts upstream of or within leukotriene biosynthetic process and leukotriene production involved in inflammatory response. Located in nucleus. Is expressed in cerebral cortex; hemolymphoid system; limb long bone; liver; and vertebra. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); asthma; brain infarction (multiple); breast cancer; and cerebral palsy. Orthologous to human ALOX5AP (arachidonate 5-lipoxygenase activating protein). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |