| Protein Name | fatty acid synthase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2194 |
| Gene Symbol | FASN |
| UniProt | P49327 (FAS_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
599
Total Number of Articles : 933 |
Description |
fatty acid synthase |
| Gene Summary |
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008] |
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