Protein Name fatty acid synthase
Organism Homo sapiens
Gene ID 2194
Gene Symbol


UniProt P49327 (FAS_HUMAN)
Relationships Total Number of functionally related compound(s) : 599
Total Number of Articles : 933

fatty acid synthase

Gene Summary

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]

  • fatty acid synthase
  • 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
  • 3-oxoacyl-[acyl-carrier-protein] reductase
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