olaparib


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437 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 632
2 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 383
3 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 121
4 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 115
5 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 82
6 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 34
7 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 32
8 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 31
9 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 19
10 breast cancer 1, early onset BRCA1_MOUSE Brca1 Mus musculus 12189 100 18
11 poly(ADP-ribose) polymerase family member 12 PAR12_HUMAN PARP12 Homo sapiens 64761 42 14
12 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 12
13 poly(ADP-ribose) polymerase 2 PARP2_HUMAN PARP2 Homo sapiens 10038 107 12
14 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 11
15 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 11
16 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 11
17 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 10
18 protein kinase, DNA-activated, catalytic subunit PRKDC_HUMAN PRKDC Homo sapiens 5591 418 9
19 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 8
20 tumor protein p53 binding protein 1 TP53B_HUMAN TP53BP1 Homo sapiens 7158 156 7
21 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 7
22 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 7
23 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 6
24 partner and localizer of BRCA2 PALB2_HUMAN PALB2 Homo sapiens 79728 35 6
25 BRCA1 associated protein 1 BAP1_HUMAN BAP1 Homo sapiens 8314 87 5
26 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 5
27 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 5
28 X-ray repair cross complementing 1 XRCC1_HUMAN XRCC1 Homo sapiens 7515 281 5
29 forkhead box M1 FOXM1_HUMAN FOXM1 Homo sapiens 2305 352 5
30 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 5
31 WEE1 G2 checkpoint kinase WEE1_HUMAN WEE1 Homo sapiens 7465 177 5
32 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 5
33 jumping translocation breakpoint JTB_HUMAN JTB Homo sapiens 10899 104 4
34 schlafen family member 11 SLN11_HUMAN SLFN11 Homo sapiens 91607 41 4
35 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 4
36 breast cancer 2, early onset BRCA2_MOUSE Brca2 Mus musculus 12190 37 4
37 ataxia telangiectasia mutated ATM_MOUSE Atm Mus musculus 11920 222 4
38 bromodomain containing 4 BRD4_HUMAN BRD4 Homo sapiens 23476 360 4
39 apurinic/apyrimidinic endodeoxyribonuclease 1 APEX1_HUMAN APEX1 Homo sapiens 328 528 4
40 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 4
41 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 4
42 RAD51 paralog C RA51C_HUMAN RAD51C Homo sapiens 5889 22 4
43 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 4
44 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 4
45 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 3
46 poly (ADP-ribose) polymerase family, member 12 PAR12_MOUSE Parp12 Mus musculus 243771 10 3
47 myeloperoxidase PERM_MOUSE Mpo Mus musculus 17523 1067 3
48 poly (ADP-ribose) polymerase 1 PARP1_RAT Parp1 Rattus norvegicus 25591 495 3
49 phosphatase and tensin homolog PTEN_MOUSE Pten Mus musculus 19211 532 3
50 microtubule associated protein 1 light chain 3 alpha MLP3A_HUMAN MAP1LC3A Homo sapiens 84557 710 3