| Protein Name | bromodomain containing 4 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 23476 |
| Gene Symbol | BRD4 |
| UniProt | O60885 (BRD4_HUMAN), A0A024R7H8 (A0A024R7H8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
360
Total Number of Articles : 412 |
Description |
bromodomain containing 4 |
| Gene Summary |
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] |
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