olaparib

ATR serine/threonine kinase ; Homo sapiens







12 Article(s)
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1 34969765 Olaparib-induced Apoptosis Through EBNA1-ATR-p38 MAPK Signaling Pathway in Epstein-Barr Virus-positive Gastric Cancer Cells. 2022 Jan 4
2 35051747 Recent advances in DDR (DNA damage response) inhibitors for cancer therapy. 2022 Feb 15 1
3 35078817 ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib. 2022 Mar 15 1
4 33268569 Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer. 2021 Feb 2
5 34082024 ATR inhibition amplifies antitumor effects of olaparib in biliary tract cancer. 2021 Sep 28 2
6 34280886 MTA2 sensitizes gastric cancer cells to PARP inhibition by induction of DNA replication stress. 2021 Oct 1
7 34527850 Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations). 2021 1
8 34761497 MET inhibition enhances PARP inhibitor efficacy in castration-resistant prostate cancer by suppressing the ATM/ATR and PI3K/AKT pathways. 2021 Dec 1
9 34944835 Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells. 2021 Dec 10 2
10 33352723 PARP Inhibition Increases the Reliance on ATR/CHK1 Checkpoint Signaling Leading to Synthetic Lethality-An Alternative Treatment Strategy for Epithelial Ovarian Cancer Cells Independent from HR Effectiveness. 2020 Dec 19 3
11 31529615 Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells. 2019 Nov 4
12 26097887 A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells. 2015 1