navitoclax


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85 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 101
2 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 61
3 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 20
4 BCL2 like 2 B2CL2_HUMAN BCL2L2 Homo sapiens 599 68 17
5 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 13
6 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 6
7 BCL2-like 1 B2CL1_MOUSE Bcl2l1 Mus musculus 12048 377 6
8 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 6
9 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
10 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 3
11 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 2
12 BCL2-like 2 B2CL2_MOUSE Bcl2l2 Mus musculus 12050 18 2
13 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 2
14 BCL2 antagonist/killer 1 BAK_HUMAN BAK1 Homo sapiens 578 490 2
15 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 2
16 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2
17 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
18 phorbol-12-myristate-13-acetate-induced protein 1 APR_HUMAN PMAIP1 Homo sapiens 5366 357 2
19 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 2
20 BTB domain containing 10 BTBDA_HUMAN BTBD10 Homo sapiens 84280 7 1
21 SCLC1 - SCLC1 Homo sapiens 7864 68 1
22 exportin 1 XPO1_HUMAN XPO1 Homo sapiens 7514 208 1
23 hepatocyte growth factor HGF_MOUSE Hgf Mus musculus 15234 356 1
24 aryl-hydrocarbon receptor AHR_MOUSE Ahr Mus musculus 11622 793 1
25 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 1
26 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 1
27 chromobox 8 CBX8_HUMAN CBX8 Homo sapiens 57332 830 1
28 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 1
29 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 1
30 Kirsten rat sarcoma viral oncogene homolog RASK_MOUSE Kras Mus musculus 16653 464 1
31 lysine acetyltransferase 2B KAT2B_HUMAN KAT2B Homo sapiens 8850 295 1
32 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 1
33 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 1
34 mucin 5AC, oligomeric mucus/gel-forming MUC5A_HUMAN MUC5AC Homo sapiens 4586 437 1
35 tyrosyl-tRNA synthetase 1 SYYC_HUMAN YARS1 Homo sapiens 8565 45 1
36 T-box transcription factor 1 TBX1_HUMAN TBX1 Homo sapiens 6899 869 1
37 tenascin C TENA_MOUSE Tnc Mus musculus 21923 113 1
38 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 1
39 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 1
40 p21 (RAC1) activated kinase 3 PAK3_HUMAN PAK3 Homo sapiens 5063 51 1
41 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 1
42 cyclin dependent kinase inhibitor 2A ARF_MOUSE Cdkn2a Mus musculus 12578 200 1
43 cyclin dependent kinase 9 CDK9_HUMAN CDK9 Homo sapiens 1025 239 1
44 ATPase plasma membrane Ca2+ transporting 2 AT2B2_HUMAN ATP2B2 Homo sapiens 491 164 1
45 lysine methyltransferase 2A KMT2A_HUMAN KMT2A Homo sapiens 4297 332 1
46 carboxypeptidase D CBPD_HUMAN CPD Homo sapiens 1362 53 1
47 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 1
48 interleukin 13 IL13_HUMAN IL13 Homo sapiens 3596 698 1
49 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
50 mitochondrial antiviral signaling protein MAVS_HUMAN MAVS Homo sapiens 57506 133 1