Topotecan


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290 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 116
2 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 38
3 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 23
4 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 21
5 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 19
6 DNA topoisomerase I TOP1_HUMAN TOP1 Homo sapiens 7150 98 15
7 colony stimulating factor 3 CSF3_HUMAN CSF3 Homo sapiens 1440 955 13
8 tyrosyl-DNA phosphodiesterase 1 TYDP1_HUMAN TDP1 Homo sapiens 55775 208 12
9 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 11
10 SCLC1 - SCLC1 Homo sapiens 7864 68 10
11 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 9
12 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 9
13 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 8
14 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 8
15 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 7
16 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 7
17 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 6
18 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 6
19 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
20 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
21 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 5
22 ubiquitin protein ligase E3A UBE3A_MOUSE Ube3a Mus musculus 22215 25 5
23 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 5
24 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 5
25 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 5
26 ATP binding cassette subfamily B member 6 (Langereis blood group) ABCB6_HUMAN ABCB6 Homo sapiens 10058 793 5
27 colony stimulating factor 2 CSF2_HUMAN CSF2 Homo sapiens 1437 2088 5
28 hypoxia inducible factor 1, alpha subunit HIF1A_MOUSE Hif1a Mus musculus 15251 724 4
29 host cell factor C1 HCFC1_HUMAN HCFC1 Homo sapiens 3054 516 4
30 ATP binding cassette subfamily G member 2 Q38JL0_CANLF ABCG2 Canis lupus familiaris 478472 141 4
31 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 4
32 topoisomerase (DNA) I TOP1_MOUSE Top1 Mus musculus 21969 54 4
33 MYCN proto-oncogene, bHLH transcription factor MYCN_HUMAN MYCN Homo sapiens 4613 374 4
34 tyrosyl-DNA phosphodiesterase 1 B8JJC1_MOUSE Tdp1 Mus musculus 104884 22 4
35 choline phosphotransferase 1 CHPT1_HUMAN CHPT1 Homo sapiens 56994 212 4
36 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 4
37 metallothionein 1E MT1E_HUMAN MT1E Homo sapiens 4493 133 4
38 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 3
39 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 3
40 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 3
41 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 3
42 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 3
43 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 3
44 schlafen family member 11 SLN11_HUMAN SLFN11 Homo sapiens 91607 41 3
45 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 3
46 RB transcriptional corepressor 1 RB_HUMAN RB1 Homo sapiens 5925 809 3
47 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 3
48 Fas ligand TNFL6_HUMAN FASLG Homo sapiens 356 783 3
49 chromobox 8 CBX8_HUMAN CBX8 Homo sapiens 57332 830 3
50 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 3