| Protein Name | MYCN proto-oncogene, bHLH transcription factor |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4613 |
| Gene Symbol | MYCN |
| UniProt | P04198 (MYCN_HUMAN), A0A1W2PPD9 (A0A1W2PPD9_HUMAN), Q9H224 (Q9H224_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
374
Total Number of Articles : 475 |
Description |
MYCN proto-oncogene, bHLH transcription factor |
| Gene Summary |
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
| synonyms |
|
| Properties | |