Protein Name MYCN proto-oncogene, bHLH transcription factor
Organism Homo sapiens
Gene ID 4613
Gene Symbol


UniProt P04198 (MYCN_HUMAN), A0A1W2PPD9 (A0A1W2PPD9_HUMAN), Q9H224 (Q9H224_HUMAN)
Relationships Total Number of functionally related compound(s) : 374
Total Number of Articles : 475

MYCN proto-oncogene, bHLH transcription factor

Gene Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

  • N-myc proto-oncogene protein
  • class E basic helix-loop-helix protein 37
  • neuroblastoma MYC oncogene
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