Topotecan

tyrosyl-DNA phosphodiesterase 1 ; Homo sapiens







12 Article(s)
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1 35429714 Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity. 2022 Jun 1
2 34073771 Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments. 2021 May 24 2
3 34159519 Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs. 2021 Dec 5
4 34356597 New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition. 2021 Jul 1 1
5 34768766 New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1. 2021 Oct 20 1
6 33263997 Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I. 2020 Dec 16 2
7 31878088 Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy. 2019 Dec 23 2
8 30191738 Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy. 2018 Dec 1
9 27893431 Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin. 2016 Dec 27 1
10 25232464 TDP1/TOP1 Ratio as a Promising Indicator for the Response of Small Cell Lung Cancer to Topotecan. 2014 Jul 25 3
11 19883083 4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors. 2009 Nov 26 1
12 20301284 Spinocerebellar Ataxia with Axonal Neuropathy, Autosomal Recessive – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY 1993 1