Eicosanoids


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705 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 phospholipase A2 group IB PA21B_HUMAN PLA2G1B Homo sapiens 5319 1857 139
2 phospholipase A2 group IVA PA24A_HUMAN PLA2G4A Homo sapiens 5321 664 102
3 mitochondrially encoded cytochrome c oxidase II COX2_HUMAN COX2 Homo sapiens 4513 5330 72
4 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 66
5 arachidonate 5-lipoxygenase LOX5_HUMAN ALOX5 Homo sapiens 240 1110 66
6 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 52
7 phospholipase A2, group IVA (cytosolic, calcium-dependent) PA24A_MOUSE Pla2g4a Mus musculus 18783 276 42
8 phospholipase A2 group IIA PA2GA_HUMAN PLA2G2A Homo sapiens 5320 580 39
9 phospholipase A2 group IB PA21B_RAT Pla2g1b Rattus norvegicus 29526 912 32
10 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 31
11 mitochondrially encoded cytochrome c oxidase I COX1_HUMAN COX1 Homo sapiens 4512 1134 28
12 peroxisome proliferator activated receptor gamma PPARG_HUMAN PPARG Homo sapiens 5468 2156 28
13 pumilio RNA binding family member 3 PUM3_HUMAN PUM3 Homo sapiens 9933 620 28
14 PCNA clamp associated factor PAF15_RAT Pclaf Rattus norvegicus 300795 777 25
15 arachidonate 15-lipoxygenase LOX15_HUMAN ALOX15 Homo sapiens 246 495 25
16 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 25
17 peroxisome proliferator activated receptor alpha PPARA_HUMAN PPARA Homo sapiens 5465 1347 24
18 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 23
19 PCNA clamp associated factor PAF15_HUMAN PCLAF Homo sapiens 9768 1129 23
20 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 23
21 phospholipase A2, group IB, pancreas PA21B_MOUSE Pla2g1b Mus musculus 18778 414 22
22 prostaglandin E synthase PTGES_MOUSE Ptges Mus musculus 64292 448 20
23 coagulation factor II, thrombin THRB_HUMAN F2 Homo sapiens 2147 4706 18
24 cytochrome c oxidase II, mitochondrial COX2_MOUSE COX2 Mus musculus 17709 1349 17
25 prostaglandin-endoperoxide synthase 1 PGH1_HUMAN PTGS1 Homo sapiens 5742 531 17
26 phospholipase A2 group X PA2GX_HUMAN PLA2G10 Homo sapiens 8399 210 16
27 arachidonate 15-lipoxygenase LOX15_MOUSE Alox15 Mus musculus 11687 179 16
28 prostaglandin D2 synthase PTGDS_HUMAN PTGDS Homo sapiens 5730 397 15
29 epoxide hydrolase 2 HYES_HUMAN EPHX2 Homo sapiens 2053 480 14
30 arachidonate 5-lipoxygenase LOX5_MOUSE Alox5 Mus musculus 11689 283 14
31 cytochrome P450 family 2 subfamily B member 6 CP2B6_HUMAN CYP2B6 Homo sapiens 1555 1488 13
32 cytochrome P450, family 2, subfamily g, polypeptide 1 CP2G1_RAT Cyp2g1 Rattus norvegicus 25251 2275 13
33 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 12
34 phospholipase A2, group IIA (platelets, synovial fluid) PA2GA_MOUSE Pla2g2a Mus musculus 18780 148 12
35 arachidonate 5-lipoxygenase LOX5_RAT Alox5 Rattus norvegicus 25290 439 12
36 insulin INS_HUMAN INS Homo sapiens 3630 7950 11
37 endothelin 1 EDN1_HUMAN EDN1 Homo sapiens 1906 1547 11
38 epoxide hydrolase 2, cytoplasmic HYES_MOUSE Ephx2 Mus musculus 13850 375 11
39 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 11
40 phospholipase A2, group V PA2G5_MOUSE Pla2g5 Mus musculus 18784 176 10
41 phospholipase A2 group VI PLPL9_HUMAN PLA2G6 Homo sapiens 8398 190 10
42 kininogen 1 KNG1_HUMAN KNG1 Homo sapiens 3827 1580 10
43 phospholipase A2 group IVA Q6IRF5_RAT Pla2g4a Rattus norvegicus 24653 249 9
44 lysyl oxidase LYOX_HUMAN LOX Homo sapiens 4015 567 9
45 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 9
46 prostaglandin-endoperoxide synthase 2 PGH2_RAT Ptgs2 Rattus norvegicus 29527 1161 9
47 endothelin-1 A0A286XTW8_CAVPO Edn1 Cavia porcellus 100726197 159 8
48 phospholipase A2 group IID PA2GD_HUMAN PLA2G2D Homo sapiens 26279 85 8
49 carbonyl reductase 1 CBR1_HUMAN CBR1 Homo sapiens 873 414 8
50 cytochrome c oxidase I, mitochondrial COX1_MOUSE COX1 Mus musculus 17708 283 8