Protein Name phospholipase A2 group VI
Organism Homo sapiens
Gene ID 8398
Gene Symbol

PLA2G6

UniProt O60733 (PLPL9_HUMAN)
Relationships Total Number of functionally related compound(s) : 190
Total Number of Articles : 258
Description

phospholipase A2 group VI

Gene Summary

The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]

synonyms
  • 85/88 kDa calcium-independent phospholipase A2
  • 2-lysophosphatidylcholine acylhydrolase
  • 85 kDa calcium-independent phospholipase A2
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Properties