Protein Name arachidonate 15-lipoxygenase
Organism Homo sapiens
Gene ID 246
Gene Symbol

ALOX15

UniProt P16050 (LOX15_HUMAN)
Relationships Total Number of functionally related compound(s) : 495
Total Number of Articles : 531
Description

arachidonate 15-lipoxygenase

Gene Summary

This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]

synonyms
  • polyunsaturated fatty acid lipoxygenase ALOX15
  • 12/15-lipoxygenase
  • 15-LOX type 1
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Properties