Eicosanoids

phospholipase A2, group IVA (cytosolic, calcium-dependent) ; Mus musculus







42 Article(s)
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1 35219746 Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1. 2022 Apr 1
2 35367992 Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury. 2022 Apr 1 1
3 30794438 β-Arrestin-2-ERK1/2 cPLA2α axis mediates TLR4 signaling to influence eicosanoid induction in ischemic brain. 2019 May 2
4 31129176 Respective contribution of cytosolic phospholipase A2α and secreted phospholipase A2 IIA to inflammation and eicosanoid production in arthritis. 2019 Aug 2
5 31796632 The interaction of ceramide 1-phosphate with group IVA cytosolic phospholipase A2 coordinates acute wound healing and repair. 2019 Dec 3 2
6 29229740 Bone marrow-derived cPLA2α contributes to renal fibrosis progression. 2018 Feb 3
7 26045535 Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension. 2016 Feb 1
8 27501951 Cytosolic phospholipase A2 contributes to innate immune defense against Candida albicans lung infection. 2016 Aug 8 1
9 25460828 The role of PGE2 in intestinal inflammation and tumorigenesis. 2015 Jan-Mar 1
10 25667212 Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology. 2015 Apr 2
11 26520095 Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway. 2015 Oct 31 2
12 24366870 Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages. 2014 Feb 14 1
13 23376443 Leptin attenuates lipopolysaccharide-induced apoptosis of thymocytes partially via down-regulation of cPLA2 and p38 MAPK activation. 2013 Mar 1
14 24244531 Eicosanoid profiling in an orthotopic model of lung cancer progression by mass spectrometry demonstrates selective production of leukotrienes by inflammatory cells of the microenvironment. 2013 2
15 21350197 Cytosolic phospholipase A2alpha contributes to blood pressure increases and endothelial dysfunction under chronic NO inhibition. 2011 May 1
16 21454644 CD36 protein is involved in store-operated calcium flux, phospholipase A2 activation, and production of prostaglandin E2. 2011 May 20 1
17 21884509 Cytosolic phospholipase A(2)α protects against ischemia/reperfusion injury in the heart. 2011 Aug 2
18 19655230 Cytosolic phospholipase A2 alpha inhibitor, pyrroxyphene, displays anti-arthritic and anti-bone destructive action in a murine arthritis model. 2010 Jan 1
19 20226226 Localization and function of cytosolic phospholipase A2alpha at the Golgi. 2010 Jun 1
20 19632995 Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. 2009 Sep 25 3
21 18287786 Inhibitory effect of a potent and selective cytosolic phospholipase A2alpha inhibitor RSC-3388 on skin inflammation in mice. 2008 1
22 18550790 Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages. 2008 Sep 1
23 17293613 Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts. 2007 Apr 20 2
24 17369491 Group V secretory PLA2 regulates TLR2-dependent eicosanoid generation in mouse mast cells through amplification of ERK and cPLA2alpha activation. 2007 Jul 15 4
25 17229087 Cytosolic phospholipase A alpha modulates NMDA neurotoxicity in mouse hippocampal cultures. 2006 Dec 1
26 15718387 Cytosolic phospholipase A2alpha regulates induction of brain cyclooxygenase-2 in a mouse model of inflammation. 2005 Jun 1
27 15789617 Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2 alpha. 2005 Jan 1
28 15805260 Cytoplasmic phospholipase A2 deletion enhances colon tumorigenesis. 2005 Apr 1 1
29 14713302 The expression of brain cyclooxygenase-2 is down-regulated in the cytosolic phospholipase A2 knockout mouse. 2003 Dec 1
30 12664562 Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. 2002 1
31 11517434 Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes. 2001 Sep 15 1
32 10783127 Matrix-associated transforming growth factor-beta1 primes mouse bone marrow-derived mast cells for increased high-affinity Fc receptor for immunoglobulin E-dependent eicosanoid biosynthesis. 2000 May 1
33 10867029 Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation. 2000 Jun 30 2
34 10913368 Activation of ERK1/2 and cPLA(2) by the p55 TNF receptor occurs independently of FAN. 2000 Aug 2 1
35 10962291 Increased cyclooxygenase-2 and 5-lipoxygenase activating protein expression in peritoneal macrophages during ovalbumin immunization of mice and cytosolic phospholipase A(2) activation after antigen challenge. 2000 Aug 24 1
36 11080683 Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockouts. 2000 Oct 31 1
37 10220374 Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells. 1999 Apr 27 3
38 10417811 Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration. 1999 Aug 1
39 10521702 IL-13 induces serine phosphorylation of cPLA2 in mouse peritoneal macrophages leading to arachidonic acid and PGE2 production and blocks the zymosan-induced serine phosphorylation of cPLA2 and eicosanoid production. 1999 Sep 22 2
40 9330788 Arachidonic acid mediates calcium influx induced by basic fibroblast growth factor in Balb-c 3T3 fibroblasts. 1997 Sep 2
41 7541141 Interleukin 4 suppresses c-kit ligand-induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow-derived mast cells. 1995 Jun 20 1
42 7517423 Dual regulation of cytosolic phospholipase A2 in mast cells after cross-linking of FC epsilon-receptor. 1994 Jul 15 1