niraparib


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89 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 109
2 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 33
3 poly(ADP-ribose) polymerase 2 PARP2_HUMAN PARP2 Homo sapiens 10038 107 13
4 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 7
5 poly(ADP-ribose) polymerase family member 12 PAR12_HUMAN PARP12 Homo sapiens 64761 42 6
6 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 5
7 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 5
8 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
9 proline rich membrane anchor 1 PRIMA_HUMAN PRIMA1 Homo sapiens 145270 54 3
10 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 3
11 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 3
12 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 3
13 unc-51 like autophagy activating kinase 1 ULK1_HUMAN ULK1 Homo sapiens 8408 234 3
14 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 2
15 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 2
16 poly (ADP-ribose) polymerase family, member 12 PAR12_MOUSE Parp12 Mus musculus 243771 10 2
17 RAD51 paralog C RA51C_HUMAN RAD51C Homo sapiens 5889 22 2
18 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 2
19 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 2
20 antigen identified by monoclonal antibody Ki 67 KI67_MOUSE Mki67 Mus musculus 17345 411 2
21 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 2
22 RB transcriptional corepressor 1 RB_HUMAN RB1 Homo sapiens 5925 809 1
23 macrophage migration inhibitory factor MIF_HUMAN MIF Homo sapiens 4282 593 1
24 deoxycytidine kinase DCK_HUMAN DCK Homo sapiens 1633 234 1
25 twist family bHLH transcription factor 1 TWST1_HUMAN TWIST1 Homo sapiens 7291 370 1
26 tankyrase TNKS1_HUMAN TNKS Homo sapiens 8658 163 1
27 Fas cell surface death receptor TNR6_HUMAN FAS Homo sapiens 355 474 1
28 v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived MYCN_MOUSE Mycn Mus musculus 18109 102 1
29 CASP8 and FADD like apoptosis regulator CFLAR_HUMAN CFLAR Homo sapiens 8837 339 1
30 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 1
31 stimulator of interferon response cGAMP interactor 1 STING_MOUSE Sting1 Mus musculus 72512 62 1
32 iduronate 2-sulfatase IDS_HUMAN IDS Homo sapiens 3423 115 1
33 proline rich acidic protein 1 PRAP1_HUMAN PRAP1 Homo sapiens 118471 172 1
34 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 1
35 polo like kinase 1 PLK1_HUMAN PLK1 Homo sapiens 5347 475 1
36 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 1
37 Pim-3 proto-oncogene, serine/threonine kinase PIM3_HUMAN PIM3 Homo sapiens 415116 32 1
38 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 1
39 epiregulin EREG_HUMAN EREG Homo sapiens 2069 498 1
40 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 1
41 C-X-C motif chemokine ligand 10 CXL10_HUMAN CXCL10 Homo sapiens 3627 673 1
42 H2A.X variant histone H2AX_MOUSE H2ax Mus musculus 15270 247 1
43 dual specificity tyrosine phosphorylation regulated kinase 1A DYR1A_HUMAN DYRK1A Homo sapiens 1859 187 1
44 solute carrier family 13 member 5 S13A5_HUMAN SLC13A5 Homo sapiens 284111 79 1
45 MPL proto-oncogene, thrombopoietin receptor TPOR_HUMAN MPL Homo sapiens 4352 163 1
46 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 1
47 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 1
48 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
49 sirtuin 3 SIR3_HUMAN SIRT3 Homo sapiens 23410 319 1
50 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 1