niraparib

BRCA1 DNA repair associated ; Homo sapiens







33 Article(s)
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1 34958553 Proteomic Analysis Reveals Low-Dose PARP Inhibitor-Induced Differential Protein Expression in BRCA1-Mutated High-Grade Serous Ovarian Cancer Cells. 2022 Feb 2 1
2 35205643 Precision Medicine for BRCA/PALB2-Mutated Pancreatic Cancer and Emerging Strategies to Improve Therapeutic Responses to PARP Inhibition. 2022 Feb 11 1
3 35359396 Case Report: Niraparib-Related Pulmonary Embolism During the Treatment of BRCA Mutant Advanced Ovarian Cancer. 2022 2
4 35557035 Phase II study of niraparib in recurrent or persistent rare fraction of gynecologic malignancies with homologous recombination deficiency (JGOG2052). 2022 May 3 1
5 33453391 Niraparib maintenance therapy in patients with platinum-sensitive recurrent ovarian cancer using an individualized starting dose (NORA): a randomized, double-blind, placebo-controlled phase III trial. 2021 Apr 1
6 33545804 Successful treatment of a patient with brain metastases from endometrial cancer using Niraparib: a case report. 2021 Jan 2
7 34301749 Niraparib for Advanced Breast Cancer with Germline BRCA1 and BRCA2 Mutations: the EORTC 1307-BCG/BIG5-13/TESARO PR-30-50-10-C BRAVO Study. 2021 Oct 15 2
8 34768353 Results of a 2021 French National Survey on Management of Patients with Advanced Stage Epithelial Ovarian Cancer. 2021 Oct 21 1
9 34925959 The Overtreatment and Cost Effectiveness of Primary versus Secondary Maintenance Therapy with Poly-Adenosine Ribose Phosphate Inhibitors (PARPi) for Epithelial Ovarian Cancer (EOC). 2021 1
10 31876893 BRCA Mutations and Homologous Recombination Repair Deficiency in Treatment With Niraparib Combined With Pembrolizumab-Reply. 2020 Mar 1 1
11 31876918 BRCA Mutations and Homologous Recombination Repair Deficiency in Treatment With Niraparib Combined With Pembrolizumab. 2020 Mar 1 1
12 32173049 Cost-effectiveness of niraparib, rucaparib, and olaparib for treatment of platinum-resistant, recurrent ovarian carcinoma. 2020 May 1
13 32371137 'PARP'ing fibrosis: repurposing poly (ADP ribose) polymerase (PARP) inhibitors. 2020 Jul 1
14 32717529 The ups and downs of Poly(ADP-ribose) Polymerase-1 inhibitors in cancer therapy-Current progress and future direction. 2020 Oct 1 1
15 32963528 BRCA Mutations in Prostate Cancer: Prognostic and Predictive Implications. 2020 1
16 30824427 Niraparib Shrinks BRCA-Mutated Prostate Tumors. 2019 Apr 1
17 30948273 Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial. 2019 May 2
18 31191001 Current status and future prospects of PARP inhibitor clinical trials in ovarian cancer. 2019 1
19 31194225 Open-label Clinical Trial of Niraparib Combined With Pembrolizumab for Treatment of Advanced or Metastatic Triple-Negative Breast Cancer. 2019 Aug 1 1
20 31466953 Niraparib as maintenance therapy in a patient with ovarian cancer and brain metastases. 2019 Aug 28 1
21 31562799 Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. 2019 Dec 19 1
22 32642648 Efficacy and pharmacodynamics of niraparib in BRCA-mutant and wild-type intracranial triple-negative breast cancer murine models. 2019 May-Dec 3
23 33343988 Rucaparib and Niraparib in Advanced Ovarian Cancer. 2019 May-Jun 2
24 29397193 The poly (ADP ribose) polymerase inhibitor niraparib: Management of toxicities. 2018 Apr 2
25 29605737 Rucaparib: An emerging parp inhibitor for treatment of recurrent ovarian cancer. 2018 May 1
26 29911447 Niraparib for the treatment of ovarian cancer. 2018 Aug 1
27 30647846 A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models. 2018 Dec 14 2
28 28631775 [Innovations in the treatment of ovarian cancer. Analysis of the therapeutic development: from platinum to immunotherapy.] 2017 Jun 1
29 29081841 Niraparib in ovarian cancer: results to date and clinical potential. 2017 Sep 1
30 29138572 Current status of poly(ADP-ribose) polymerase inhibitors and future directions. 2017 1
31 29214031 PARP inhibitors as potential therapeutic agents for various cancers: focus on niraparib and its first global approval for maintenance therapy of gynecologic cancers. 2017 1
32 23810788 The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial. 2013 Aug 4
33 19873981 Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. 2009 Nov 26 2