Protein Name C-X-C motif chemokine ligand 10
Organism Homo sapiens
Gene ID 3627
Gene Symbol

CXCL10

UniProt P02778 (CXL10_HUMAN)
Relationships Total Number of functionally related compound(s) : 673
Total Number of Articles : 860
Description

C-X-C motif chemokine ligand 10

Gene Summary

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]

synonyms
  • C-X-C motif chemokine 10
  • 10 kDa interferon gamma-induced protein
  • gamma IP10
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Properties