Mevalonic Acid


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557 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 3-hydroxy-3-methylglutaryl-CoA reductase HMDH_HUMAN HMGCR Homo sapiens 3156 571 239
2 farnesyl diphosphate synthase FPPS_HUMAN FDPS Homo sapiens 2224 223 70
3 3-hydroxy-3-methylglutaryl-CoA reductase HMDH_RAT Hmgcr Rattus norvegicus 25675 353 49
4 3-hydroxy-3-methylglutaryl-Coenzyme A reductase HMDH_MOUSE Hmgcr Mus musculus 15357 170 42
5 mevalonate kinase KIME_HUMAN MVK Homo sapiens 4598 138 31
6 ras homolog family member A RHOA_HUMAN RHOA Homo sapiens 387 835 24
7 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 18
8 farnesyl diphosphate synthetase FPPS_MOUSE Fdps Mus musculus 110196 34 17
9 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 16
10 sterol regulatory element binding transcription factor 2 SRBP2_HUMAN SREBF2 Homo sapiens 6721 209 14
11 high mobility group AT-hook 1 HMGA1_HUMAN HMGA1 Homo sapiens 3159 170 14
12 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 13
13 low density lipoprotein receptor LDLR_HUMAN LDLR Homo sapiens 3949 826 13
14 hydroxy methylglutaryl CoA reductase 1 HMDH1_ARATH HMG1 Arabidopsis thaliana 843982 25 13
15 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 12
16 geranylgeranyl diphosphate synthase 1 GGPPS_HUMAN GGPS1 Homo sapiens 9453 49 12
17 HRas proto-oncogene, GTPase RASH_HUMAN HRAS Homo sapiens 3265 553 10
18 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMDH_CRIGR Hmgcr Cricetulus griseus 100756363 41 10
19 phosphomevalonate kinase PMVK_HUMAN PMVK Homo sapiens 10654 31 9
20 3-hydroxy-3-methylglutaryl-CoA synthase 1 HMCS1_HUMAN HMGCS1 Homo sapiens 3157 42 8
21 insulin INS_HUMAN INS Homo sapiens 3630 7950 8
22 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 8
23 farnesyl diphosphate synthase FPPS_RAT Fdps Rattus norvegicus 83791 49 8
24 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 8
25 RAP1A, member of RAS oncogene family RAP1A_HUMAN RAP1A Homo sapiens 5906 263 7
26 HMG Coenzyme A reductase HMDH_DROME Hmgcr Drosophila melanogaster 42803 14 7
27 tafazzin, phospholipid-lysophospholipid transacylase TAZ_HUMAN TAFAZZIN Homo sapiens 6901 297 7
28 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 7
29 farnesyl-diphosphate farnesyltransferase 1 FDFT_HUMAN FDFT1 Homo sapiens 2222 151 7
30 bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase FPPS_YEAST ERG20 Saccharomyces cerevisiae S288C 853272 44 7
31 serpin family E member 1 PAI1_HUMAN SERPINE1 Homo sapiens 5054 1182 6
32 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 6
33 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 6
34 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 6
35 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 6
36 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 6
37 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 6
38 nitric oxide synthase 3 NOS3_HUMAN NOS3 Homo sapiens 4846 1142 5
39 hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 HMDH1_YEAST HMG1 Saccharomyces cerevisiae S288C 854900 22 5
40 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 5
41 GLI family zinc finger 2 GLI2_HUMAN GLI2 Homo sapiens 2736 1670 5
42 caspase 1 CASP1_HUMAN CASP1 Homo sapiens 834 952 5
43 bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase FDFT_YEAST ERG9 Saccharomyces cerevisiae S288C 856597 48 5
44 coagulation factor III, tissue factor TF_HUMAN F3 Homo sapiens 2152 916 5
45 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 5
46 acetyl-CoA C-acetyltransferase THIL_YEAST ERG10 Saccharomyces cerevisiae S288C 856079 18 5
47 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 5
48 3-hydroxy-3-methylglutaryl-CoA synthase 2 HMCS2_HUMAN HMGCS2 Homo sapiens 3158 64 5
49 ras homolog family member B RHOB_HUMAN RHOB Homo sapiens 388 154 5
50 mevalonate kinase KIME_RAT Mvk Rattus norvegicus 81727 24 5