| 1 |
34711640 | Intracellular Cholesterol Pools Regulate Oncogenic Signaling and Epigenetic Circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia. | 2022 Mar 1 |
2 |
| 2 |
35193687 | Combined inhibition of HMGCoA reductase and mitochondrial complex I induces tumor regression of BRAF inhibitor-resistant melanomas. | 2022 Feb 22 |
1 |
| 3 |
35321818 | Molecular targets of statins and their potential side effects: Not all the glitter is gold. | 2022 May 5 |
2 |
| 4 |
35359411 | Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma. | 2022 |
1 |
| 5 |
35470784 | Effect of pH on structural dynamics of HMG-CoA reductase and binding affinity to β-sitosterol. | 2022 Apr 26 |
2 |
| 6 |
35538051 | Statin therapy inhibits fatty acid synthase via dynamic protein modifications. | 2022 May 10 |
2 |
| 7 |
33307558 | Role of the Mevalonate Pathway in Adrenocortical Tumorigenesis. | 2021 Feb |
2 |
| 8 |
33992804 | Targeting cholesterol biosynthesis promotes anti-tumor immunity by inhibiting long noncoding RNA SNHG29-mediated YAP activation. | 2021 Oct 6 |
4 |
| 9 |
34627266 | Simvastatin induced ferroptosis for triple-negative breast cancer therapy. | 2021 Oct 9 |
1 |
| 10 |
34884489 | Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis. | 2021 Nov 24 |
1 |
| 11 |
31963885 | Potential Role of Tocotrienols on Non-Communicable Diseases: A Review of Current Evidence. | 2020 Jan 19 |
2 |
| 12 |
32004772 | Plasma mevalonic acid exposure as a pharmacodynamic biomarker of fluvastatin/atorvastatin in healthy volunteers. | 2020 Apr 15 |
2 |
| 13 |
32758903 | Mevalonate pathway, selenoproteins, redox balance, immune system, Covid-19: Reasoning about connections. | 2020 Nov |
1 |
| 14 |
32887721 | Statins as Anticancer Agents in the Era of Precision Medicine. | 2020 Nov 15 |
4 |
| 15 |
32974183 | Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy. | 2020 |
3 |
| 16 |
33059448 | Brassinosteroid Regulates 3-Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development. | 2020 Oct 28 |
1 |
| 17 |
33109681 | Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase. | 2020 Dec |
2 |
| 18 |
33110390 | Pleiotropic use of Statins as non-lipid-lowering drugs. | 2020 |
1 |
| 19 |
33110395 | Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis. | 2020 |
1 |
| 20 |
30551403 | MDR reversal and pro-apoptotic effects of statins and statins combined with flavonoids in colon cancer cells. | 2019 Jan |
1 |
| 21 |
30619997 | Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance. | 2019 Jan |
2 |
| 22 |
30702149 | Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme. | 2019 Mar |
2 |
| 23 |
30765461 | Statins Perturb Gβγ Signaling and Cell Behavior in a Gγ Subtype Dependent Manner. | 2019 Apr |
1 |
| 24 |
30787037 | Mevalonate signaling, COPD and cancer: the statins and beyond. | 2019 Apr |
2 |
| 25 |
30829216 | Optimization of process variables for increased production of lovastatin in Aspergillus terreus PU-PCSIR1 and its characterization. | 2019 Jan |
1 |
| 26 |
31023626 | An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer. | 2019 Jul |
4 |
| 27 |
31026757 | Transcriptome-based identification of lovastatin as a breast cancer stem cell-targeting drug. | 2019 Jun |
2 |
| 28 |
31316383 | The Impact of Mevastatin on HCV Replication and Autophagy of Non-Transformed HCV Replicon Hepatocytes Is Influenced by the Extracellular Lipid Uptake. | 2019 |
1 |
| 29 |
31455613 | Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing. | 2019 Oct |
2 |
| 30 |
31554629 | Fluvastatin Inhibits HMG-CoA Reductase and Prevents Non-Small Cell Lung Carcinogenesis. | 2019 Dec |
1 |
| 31 |
31631207 | Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target. | 2019 Nov 1 |
2 |
| 32 |
31685796 | ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma. | 2019 Nov 4 |
1 |
| 33 |
31737505 | Current perspectives on statins as potential anti-cancer therapeutics: clinical outcomes and underlying molecular mechanisms. | 2019 Oct |
2 |
| 34 |
29445111 | Fluvastatin protects cochleae from damage by high-level noise. | 2018 Feb 14 |
1 |
| 35 |
29575963 | Innovations in asthma therapy: is there a role for inhaled statins? | 2018 Jun |
1 |
| 36 |
29683099 | Identifying Potential Therapeutics for Osteoporosis by Exploiting the Relationship between Mevalonate Pathway and Bone Metabolism. | 2018 |
1 |
| 37 |
29765517 | Targeting the mevalonate pathway is a novel therapeutic approach to inhibit oncogenic FoxM1 transcription factor in human hepatocellular carcinoma. | 2018 Apr 20 |
6 |
| 38 |
29890243 | Repurposing of statins via inhalation to treat lung inflammatory conditions. | 2018 Aug |
1 |
| 39 |
29899021 | Statins enhance efficacy of venetoclax in blood cancers. | 2018 Jun 13 |
1 |
| 40 |
29923256 | Statins: a role in breast cancer therapy? | 2018 Oct |
2 |
| 41 |
30034619 | Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics. | 2018 Jun 29 |
1 |
| 42 |
30089652 | Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC). | 2018 Sep 14 |
2 |
| 43 |
30106444 | Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells. | 2018 Oct |
1 |
| 44 |
30237809 | STATINS AND BONE HEALTH: A MINI REVIEW. | 2018 Jan-Apr |
1 |
| 45 |
26758944 | The Mevalonate Pathway and Innate Immune Hyper-Responsiveness in the Pathogenesis of COPD and Lung Cancer: Potential for Chemoprevention. | 2017 |
1 |
| 46 |
26758951 | Statins, Mevalonate Pathway and its Intermediate Products in Placental Development and Preeclampsia. | 2017 |
1 |
| 47 |
28362175 | Synergistic Impact of d-δ-Tocotrienol and Geranylgeraniol on the Growth and HMG CoA Reductase of Human DU145 Prostate Carcinoma Cells. | 2017 May-Jun |
1 |
| 48 |
28668359 | The balance between induction and inhibition of mevalonate pathway regulates cancer suppression by statins: A review of molecular mechanisms. | 2017 Aug 1 |
2 |
| 49 |
28710496 | Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer. | 2017 Jul 14 |
1 |
| 50 |
29039527 | Simvastatin inhibits the expression of stemness‑related genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton. | 2017 Dec |
1 |