| 1 |
34627383 | RhoA enhances osteosarcoma resistance to MPPa-PDT via the Hippo/YAP signaling pathway. | 2021 Oct 9 |
1 |
| 2 |
30787037 | Mevalonate signaling, COPD and cancer: the statins and beyond. | 2019 Apr |
1 |
| 3 |
29255172 | Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis. | 2018 Jan |
3 |
| 4 |
29319354 | Inhibition of the RhoA/Rho-associated, coiled-coil-containing protein kinase-1 pathway is involved in the therapeutic effects of simvastatin on pulmonary arterial hypertension. | 2018 |
2 |
| 5 |
29848667 | Simvastatin interferes with cancer 'stem-cell' plasticity reducing metastasis in ovarian cancer. | 2018 Oct |
1 |
| 6 |
26758944 | The Mevalonate Pathway and Innate Immune Hyper-Responsiveness in the Pathogenesis of COPD and Lung Cancer: Potential for Chemoprevention. | 2017 |
1 |
| 7 |
29039527 | Simvastatin inhibits the expression of stemnessārelated genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton. | 2017 Dec |
1 |
| 8 |
26284584 | Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells. | 2015 Oct 6 |
3 |
| 9 |
26351364 | Xanthine-based KMUP-1 improves HDL via PPARĪ³/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss. | 2015 Nov |
1 |
| 10 |
24582560 | HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation. | 2014 Mar 28 |
1 |
| 11 |
22451024 | Inhibitory effects of simvastatin on migration and invasion of rheumatoid fibroblast-like synoviocytes by preventing geranylgeranylation of RhoA. | 2013 Feb |
1 |
| 12 |
23593363 | Zoledronic acid restores doxorubicin chemosensitivity and immunogenic cell death in multidrug-resistant human cancer cells. | 2013 |
1 |
| 13 |
22322451 | Involvement of the mevalonate pathway in the antiproliferative effect of zoledronate on ACHN renal cell carcinoma cells. | 2012 May |
2 |
| 14 |
21052011 | Simvastatin reduces lipoprotein-associated phospholipase A2 in lipopolysaccharide-stimulated human monocyte-derived macrophages through inhibition of the mevalonate-geranylgeranyl pyrophosphate-RhoA-p38 mitogen-activated protein kinase pathway. | 2011 Feb |
2 |
| 15 |
21907187 | Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. | 2011 Dec 1 |
1 |
| 16 |
19151402 | Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin. | 2009 Jun |
1 |
| 17 |
17322126 | Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. | 2007 Jun |
1 |
| 18 |
16450390 | Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma. | 2006 Jul 1 |
1 |
| 19 |
16774905 | HMG-CoA reductase inhibitor simvastatin mitigates VEGF-induced "inside-out" signaling to extracellular matrix by preventing RhoA activation. | 2006 Nov |
1 |
| 20 |
16873994 | Inhibitory effect of statins on renal epithelial-to-mesenchymal transition. | 2006 |
1 |
| 21 |
16098957 | Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway. | 2005 Dec 1 |
1 |
| 22 |
12933658 | Lovastatin induces apoptosis of anaplastic thyroid cancer cells via inhibition of protein geranylgeranylation and de novo protein synthesis. | 2003 Sep |
1 |
| 23 |
11788600 | Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB. | 2002 Mar 22 |
3 |
| 24 |
12427032 | Isoprenoids influence expression of Ras and Ras-related proteins. | 2002 Nov 19 |
1 |