Protein Name sterol regulatory element binding transcription factor 2
Organism Homo sapiens
Gene ID 6721
Gene Symbol

SREBF2

UniProt Q12772 (SRBP2_HUMAN), A0A024R1Q0 (A0A024R1Q0_HUMAN)
Relationships Total Number of functionally related compound(s) : 209
Total Number of Articles : 410
Description

sterol regulatory element binding transcription factor 2

Gene Summary

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

synonyms
  • sterol regulatory element-binding protein 2
  • class D basic helix-loop-helix protein 2
  • SREBP-2
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Properties