| 1 |
35600875 | The Role of Geranylgeraniol in Managing Bisphosphonate-Related Osteonecrosis of the Jaw. | 2022 |
1 |
| 2 |
35625883 | Targeting of Mevalonate-Isoprenoid Pathway in Acute Myeloid Leukemia Cells by Bisphosphonate Drugs. | 2022 May 16 |
1 |
| 3 |
33538531 | Key Enzymes for the Mevalonate Pathway in the Cardiovascular System. | 2021 Feb 1 |
1 |
| 4 |
34885721 | Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs. | 2021 Nov 25 |
2 |
| 5 |
32569873 | Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton. | 2020 Oct |
1 |
| 6 |
32974183 | Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy. | 2020 |
1 |
| 7 |
33479604 | Targeting prenylation inhibition through the mevalonate pathway. | 2020 Jan 1 |
1 |
| 8 |
30036888 | QSAR Models for Nitrogen Containing Monophosphonate and Bisphosphonate Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors Based on Monte Carlo Method. | 2019 Mar |
2 |
| 9 |
29080272 | 3D-QSAR, molecular docking, and ONIOM studies on the structure-activity relationships and action mechanism of nitrogen-containing bisphosphonates. | 2018 Mar |
2 |
| 10 |
29337059 | FPPS mediates TGF-β1-induced non-small cell lung cancer cell invasion and the EMT process via the RhoA/Rock1 pathway. | 2018 Feb 5 |
2 |
| 11 |
29713181 | Minodronate for the treatment of osteoporosis. | 2018 |
1 |
| 12 |
29722423 | Mutations in mevalonate pathway genes in patients with familial or sporadic porokeratosis. | 2018 Jul |
1 |
| 13 |
30096489 | Bisphosphonates: Future perspective for neurological disorders. | 2018 Oct |
1 |
| 14 |
32002964 | Bisphosphonates: Future perspective for neurological disorders. | 2018 Sep |
1 |
| 15 |
28098152 | Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. | 2017 Jan 18 |
2 |
| 16 |
28123123 | [Acute phase reaction following bisphosphonates.] | 2017 |
1 |
| 17 |
28208018 | Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. | 2017 Mar 9 |
2 |
| 18 |
28419419 | The isoprenoid derivative N6 -benzyladenosine CM223 exerts antitumor effects in glioma patient-derived primary cells through the mevalonate pathway. | 2017 Jul |
2 |
| 19 |
28777842 | [Analysis of clinical and genetic features of nine patients with disseminated superfacial actinic porokeratosis]. | 2017 Aug 10 |
1 |
| 20 |
29075041 | Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma. | 2017 Oct 26 |
2 |
| 21 |
27777393 | [Pharmacokinetics of Zoledronic acid[once-yearly bisphosphonate(intravenous infusion)].] | 2016 |
2 |
| 22 |
25541745 | Investigation of the N-BP Binding at FPPS by Combined Computational Approaches. | 2015 |
2 |
| 23 |
25862838 | Synergistic growth inhibition of PC3 prostate cancer cells with low-dose combinations of simvastatin and alendronate. | 2015 Apr |
1 |
| 24 |
26047704 | Isopentenyl pyrophosphate secreted from Zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells. | 2015 Aug 7 |
1 |
| 25 |
24172032 | Thermodynamic evaluation of the binding of bisphosphonates to human farnesyl pyrophosphate synthase. | 2014 |
2 |
| 26 |
24311107 | Polymorphisms of the farnesyl diphosphate synthase gene modulate bone changes in response to atorvastatin. | 2014 Aug |
1 |
| 27 |
24534219 | Association of farnesyl diphosphate synthase polymorphisms and response to alendronate treatment in Chinese postmenopausal women with osteoporosis. | 2014 |
2 |
| 28 |
24879560 | Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. | 2014 Jul 21 |
1 |
| 29 |
22407328 | Altered expression of farnesyl pyrophosphate synthase in prostate cancer: evidence for a role of the mevalonate pathway in disease progression? | 2013 Apr |
4 |
| 30 |
23428571 | Multi-target-directed design, syntheses, and characterization of fluorescent bisphosphonate derivatives as multifunctional enzyme inhibitors in mevalonate pathway. | 2013 Jun |
1 |
| 31 |
23533771 | Bisphosphonates and cancer: what opportunities from nanotechnology? | 2013 |
1 |
| 32 |
23794630 | Essential requirements of zoledronate-induced cytokine and γδ T cell proliferative responses. | 2013 Aug 1 |
1 |
| 33 |
24434328 | Targeting gamma delta T cells for cancer immunotherapy: bench to bedside. | 2013 Nov |
2 |
| 34 |
21864230 | The chemistry of bisphosphonates: from antiscaling agents to clinical therapeutics. | 2012 Feb |
1 |
| 35 |
23032740 | In vivo phosphoantigen levels in bisphosphonate-treated human breast tumors trigger Vγ9Vδ2 T-cell antitumor cytotoxicity through ICAM-1 engagement. | 2012 Nov 15 |
4 |
| 36 |
21111853 | Biochemical and molecular mechanisms of action of bisphosphonates. | 2011 Jul |
1 |
| 37 |
21247791 | Geranylgeraniol - a new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw. | 2011 Mar |
1 |
| 38 |
21420384 | Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells. | 2011 Apr 22 |
4 |
| 39 |
21695491 | Physiology of the aging bone and mechanisms of action of bisphosphonates. | 2011 Oct |
1 |
| 40 |
21702715 | Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010). | 2011 Sep |
4 |
| 41 |
21931292 | Expansion of human peripheral blood γδ T cells using zoledronate. | 2011 Sep 9 |
2 |
| 42 |
22013129 | Indirect stimulation of human Vγ2Vδ2 T cells through alterations in isoprenoid metabolism. | 2011 Nov 15 |
2 |
| 43 |
22091898 | Bisphosphonates and osteonecrosis of the jaw. | 2011 Dec |
1 |
| 44 |
19819230 | Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. | 2010 Mar 1 |
2 |
| 45 |
20298756 | Farnesyl diphosphate synthase attenuates paclitaxel-induced apoptotic cell death in human glioblastoma U87MG cells. | 2010 Apr 26 |
1 |
| 46 |
20544107 | Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway. | 2010 Aug 7 |
1 |
| 47 |
20722615 | Molecular targets of the nitrogen containing bisphosphonates: the molecular pharmacology of prenyl synthase inhibition. | 2010 |
1 |
| 48 |
19494338 | Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells. | 2009 Jun 15 |
1 |
| 49 |
19665949 | Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. | 2009 Oct 1 |
1 |
| 50 |
19699819 | The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. | 2009 Dec |
1 |