| Protein Name | ras homolog family member A |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 387 |
| Gene Symbol | RHOA |
| UniProt | P61586 (RHOA_HUMAN), A0A024R324 (A0A024R324_HUMAN), C9JX21 (C9JX21_HUMAN), A0A7I2YQV1 (A0A7I2YQV1_HUMAN), C9JRM1 (C9JRM1_HUMAN), B4DKN9 (B4DKN9_HUMAN), Q9BVT0 (Q9BVT0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
835
Total Number of Articles : 1808 |
Description |
ras homolog family member A |
| Gene Summary |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| synonyms |
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| Properties | |