4-hydroxy-2-nonenal


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670 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 aldehyde dehydrogenase 2, mitochondrial ALDH2_MOUSE Aldh2 Mus musculus 11669 151 29
2 aldehyde dehydrogenase 2 family member ALDH2_HUMAN ALDH2 Homo sapiens 217 330 28
3 glutathione S-transferase alpha 4 GSTA4_HUMAN GSTA4 Homo sapiens 2941 44 25
4 glutathione S-transferase, alpha 4 GSTA4_MOUSE Gsta4 Mus musculus 14860 66 24
5 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 19
6 glutathione S-transferase kappa 1 GSTK1_HUMAN GSTK1 Homo sapiens 373156 1019 18
7 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 18
8 synuclein alpha SYUA_HUMAN SNCA Homo sapiens 6622 1780 15
9 ralA binding protein 1 RBP1_HUMAN RALBP1 Homo sapiens 10928 59 15
10 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 15
11 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 14
12 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 14
13 insulin INS_HUMAN INS Homo sapiens 3630 7950 11
14 hematopoietic prostaglandin D synthase HPGDS_RAT Hpgds Rattus norvegicus 58962 946 10
15 aldehyde dehydrogenase 3 family, member A1 AL3A1_RAT Aldh3a1 Rattus norvegicus 25375 319 10
16 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 10
17 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 10
18 elastase, neutrophil expressed ELNE_HUMAN ELANE Homo sapiens 1991 945 9
19 apolipoprotein B APOB_HUMAN APOB Homo sapiens 338 1181 9
20 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 9
21 transient receptor potential cation channel subfamily A member 1 TRPA1_HUMAN TRPA1 Homo sapiens 8989 575 9
22 glutathione S-transferase alpha 4 GSTA4_RAT Gsta4 Rattus norvegicus 300850 84 8
23 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 8
24 Jun proto-oncogene, AP-1 transcription factor subunit JUN_HUMAN JUN Homo sapiens 3725 1260 8
25 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 8
26 aldo-keto reductase family 1 member B ALDR_HUMAN AKR1B1 Homo sapiens 231 1037 8
27 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 8
28 kelch like ECH associated protein 1 KEAP1_HUMAN KEAP1 Homo sapiens 9817 659 8
29 aldehyde dehydrogenase 2 family member ALDH2_RAT Aldh2 Rattus norvegicus 29539 173 8
30 transient receptor potential cation channel, subfamily A, member 1 TRPA1_MOUSE Trpa1 Mus musculus 277328 405 8
31 thioredoxin THIO_HUMAN TXN Homo sapiens 7295 989 7
32 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 7
33 glutamate-cysteine ligase catalytic subunit GSH1_HUMAN GCLC Homo sapiens 2729 379 7
34 hematopoietic prostaglandin D synthase HPGDS_MOUSE Hpgds Mus musculus 54486 453 7
35 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 6
36 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 6
37 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 6
38 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 6
39 aldehyde dehydrogenase 3 family member A1 AL3A1_HUMAN ALDH3A1 Homo sapiens 218 117 6
40 aldehyde dehydrogenase 1 family, member A1 AL1A1_RAT Aldh1a1 Rattus norvegicus 24188 99 6
41 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 6
42 aldehyde dehydrogenase family 3, subfamily A1 AL3A1_MOUSE Aldh3a1 Mus musculus 11670 172 6
43 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 5
44 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 5
45 beta-secretase 1 BACE1_HUMAN BACE1 Homo sapiens 23621 881 5
46 membrane metalloendopeptidase NEP_HUMAN MME Homo sapiens 4311 625 5
47 cytochrome P450 family 2 subfamily E member 1 CP2E1_HUMAN CYP2E1 Homo sapiens 1571 990 5
48 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 5
49 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 5
50 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5