Protein Name aldo-keto reductase family 1 member B
Organism Homo sapiens
Gene ID 231
Gene Symbol


UniProt P15121 (ALDR_HUMAN), A0A024R7A8 (A0A024R7A8_HUMAN)
Relationships Total Number of functionally related compound(s) : 1037
Total Number of Articles : 1172

aldo-keto reductase family 1 member B

Gene Summary

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]

  • aldo-keto reductase family 1 member B1
  • Lii5-2 CTCL tumor antigen
  • aldehyde reductase 1
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