N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide


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64 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 25
2 Janus kinase 1 JAK1_HUMAN JAK1 Homo sapiens 3716 379 19
3 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 7
4 activin A receptor type 1 ACVR1_HUMAN ACVR1 Homo sapiens 90 158 7
5 Janus kinase 2 JAK2_MOUSE Jak2 Mus musculus 16452 466 4
6 TANK binding kinase 1 TBK1_HUMAN TBK1 Homo sapiens 29110 252 4
7 hepcidin antimicrobial peptide HEPC_HUMAN HAMP Homo sapiens 57817 384 4
8 Janus kinase 1 B1ASP2_MOUSE Jak1 Mus musculus 16451 123 3
9 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 3
10 TANK-binding kinase 1 TBK1_MOUSE Tbk1 Mus musculus 56480 83 3
11 inhibitor of kappaB kinase epsilon IKKE_MOUSE Ikbke Mus musculus 56489 28 2
12 myelocytomatosis oncogene MYC_MOUSE Myc Mus musculus 17869 289 2
13 inhibitor of nuclear factor kappa B kinase subunit epsilon IKKE_HUMAN IKBKE Homo sapiens 9641 74 2
14 Kirsten rat sarcoma viral oncogene homolog RASK_MOUSE Kras Mus musculus 16653 464 1
15 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 1
16 interleukin 6 IL6_RAT Il6 Rattus norvegicus 24498 2269 1
17 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 1
18 Cbl proto-oncogene CBL_HUMAN CBL Homo sapiens 867 449 1
19 ATP-binding cassette, sub-family B (MDR/TAP), member 1A MDR1A_MOUSE Abcb1a Mus musculus 18671 272 1
20 cytoglobin CYGB_HUMAN CYGB Homo sapiens 114757 113 1
21 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 1
22 FMS-like tyrosine kinase 3 FLT3_MOUSE Flt3 Mus musculus 14255 153 1
23 interleukin 13 IL13_HUMAN IL13 Homo sapiens 3596 698 1
24 MPL proto-oncogene, thrombopoietin receptor TPOR_HUMAN MPL Homo sapiens 4352 163 1
25 snail family transcriptional repressor 2 SNAI2_HUMAN SNAI2 Homo sapiens 6591 312 1
26 BCR pseudogene 1 - BCRP1 Homo sapiens 644079 280 1
27 signal transducer and activator of transcription 3 STAT3_RAT Stat3 Rattus norvegicus 25125 689 1
28 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 1
29 bone morphogenetic protein 6 BMP6_HUMAN BMP6 Homo sapiens 654 119 1
30 Janus kinase 3 JAK3_HUMAN JAK3 Homo sapiens 3718 218 1
31 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 1
32 thymic stromal lymphopoietin TSLP_MOUSE Tslp Mus musculus 53603 144 1
33 CD274 antigen PD1L1_MOUSE Cd274 Mus musculus 60533 466 1
34 histone deacetylase 6 HDAC6_HUMAN HDAC6 Homo sapiens 10013 454 1
35 fms related receptor tyrosine kinase 3 FLT3_HUMAN FLT3 Homo sapiens 2322 569 1
36 suppressor of cytokine signaling 3 SOCS3_RAT Socs3 Rattus norvegicus 89829 110 1
37 signal transducer and activator of transcription 1 STAT1_HUMAN STAT1 Homo sapiens 6772 747 1
38 patatin like phospholipase domain containing 3 PLPL3_HUMAN PNPLA3 Homo sapiens 80339 100 1
39 C-C motif chemokine ligand 5 CCL5_HUMAN CCL5 Homo sapiens 6352 751 1
40 thymic stromal lymphopoietin TSLP_HUMAN TSLP Homo sapiens 85480 217 1
41 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 1
42 fms related receptor tyrosine kinase 3 ligand FLT3L_HUMAN FLT3LG Homo sapiens 2323 122 1
43 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 1
44 Janus kinase 1 G3V9W2_RAT Jak1 Rattus norvegicus 84598 86 1
45 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 1
46 inhibitor of nuclear factor kappa B kinase subunit beta IKKB_HUMAN IKBKB Homo sapiens 3551 425 1
47 interleukin 13 receptor subunit alpha 1 I13R1_HUMAN IL13RA1 Homo sapiens 3597 39 1
48 interferon gamma receptor 1 INGR1_HUMAN IFNGR1 Homo sapiens 3459 46 1
49 tyrosine kinase 2 TYK2_MOUSE Tyk2 Mus musculus 54721 50 1
50 Janus kinase 1 - JAK1 Canis lupus familiaris 442952 8 1