| Protein Name | histone deacetylase 6 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10013 |
| Gene Symbol | HDAC6 |
| UniProt | Q9UBN7 (HDAC6_HUMAN), Q9BRX7 (Q9BRX7_HUMAN), A0A024QZ26 (A0A024QZ26_HUMAN), Q9NSW6 (Q9NSW6_HUMAN), B4DZH6 (B4DZH6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
454
Total Number of Articles : 584 |
Description |
histone deacetylase 6 |
| Gene Summary |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008] |
| synonyms |
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| Properties | |