Protein Name snail family transcriptional repressor 2
Organism Homo sapiens
Gene ID 6591
Gene Symbol


UniProt O43623 (SNAI2_HUMAN)
Relationships Total Number of functionally related compound(s) : 312
Total Number of Articles : 405

snail family transcriptional repressor 2

Gene Summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

  • zinc finger protein SNAI2
  • neural crest transcription factor SLUG
  • protein snail homolog 2
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