phosphatidylinositol 3,4,5-triphosphate


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460 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 148
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 134
3 insulin INS_HUMAN INS Homo sapiens 3630 7950 45
4 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 43
5 inositol polyphosphate-5-phosphatase D SHIP1_HUMAN INPP5D Homo sapiens 3635 330 36
6 phosphatase and tensin homolog PTEN_MOUSE Pten Mus musculus 19211 532 32
7 inositol polyphosphate phosphatase like 1 SHIP2_HUMAN INPPL1 Homo sapiens 3636 107 29
8 pyruvate dehydrogenase kinase 1 PDK1_HUMAN PDK1 Homo sapiens 5163 414 26
9 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 23
10 cytohesin 3 CYH3_HUMAN CYTH3 Homo sapiens 9265 73 23
11 inositol polyphosphate-5-phosphatase D SHIP1_MOUSE Inpp5d Mus musculus 16331 100 20
12 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 17
13 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 PREX1_HUMAN PREX1 Homo sapiens 57580 52 16
14 ADP ribosylation factor 6 ARF6_HUMAN ARF6 Homo sapiens 382 162 14
15 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma PK3CG_MOUSE Pik3cg Mus musculus 30955 126 12
16 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 12
17 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 12
18 prolactin induced protein PIP_HUMAN PIP Homo sapiens 5304 583 11
19 3-phosphoinositide dependent protein kinase 1 PDPK1_HUMAN PDPK1 Homo sapiens 5170 104 11
20 Bruton tyrosine kinase BTK_HUMAN BTK Homo sapiens 695 383 11
21 coagulation factor II, thrombin THRB_HUMAN F2 Homo sapiens 2147 4706 11
22 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma PK3CG_HUMAN PIK3CG Homo sapiens 5294 232 11
23 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 10
24 ArfGAP with dual PH domains 1 ADAP1_HUMAN ADAP1 Homo sapiens 11033 26 10
25 phosphoinositide-3-kinase regulatory subunit 1 P85A_HUMAN PIK3R1 Homo sapiens 5295 224 9
26 inositol polyphosphate phosphatase-like 1 SHIP2_MOUSE Inppl1 Mus musculus 16332 47 9
27 formyl peptide receptor 1 FPR1_HUMAN FPR1 Homo sapiens 2357 1382 9
28 ArfGAP with dual PH domains 1 O88768_RAT Adap1 Rattus norvegicus 171097 23 8
29 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 8
30 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 8
31 phosphoinositide-3-kinase regulatory subunit 1 P85A_MOUSE Pik3r1 Mus musculus 18708 315 8
32 cytohesin 2 CYH2_HUMAN CYTH2 Homo sapiens 9266 120 7
33 protein kinase C zeta KPCZ_HUMAN PRKCZ Homo sapiens 5590 273 7
34 GRB2 associated binding protein 1 GAB1_HUMAN GAB1 Homo sapiens 2549 70 7
35 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 7
36 inositol polyphosphate-4-phosphatase type II B INP4B_HUMAN INPP4B Homo sapiens 8821 37 6
37 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 6
38 solute carrier family 2 member 4 GLUT4_HUMAN SLC2A4 Homo sapiens 6517 552 6
39 Phosphatase and tensin homolog Q7KMQ6_DROME Pten Drosophila melanogaster 43991 16 5
40 vav guanine nucleotide exchange factor 1 VAV_HUMAN VAV1 Homo sapiens 7409 126 5
41 ras homolog family member A RHOA_HUMAN RHOA Homo sapiens 387 835 5
42 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 ARAP3_HUMAN ARAP3 Homo sapiens 64411 11 5
43 glutamine repeat protein 1 E9Q9S8_MOUSE Glrp1 Mus musculus 14659 16 5
44 pleckstrin homology like domain family B member 2 PHLB2_HUMAN PHLDB2 Homo sapiens 90102 8 4
45 cell division cycle 42 CDC42_HUMAN CDC42 Homo sapiens 998 455 4
46 Fc gamma receptor IIa FCG2A_HUMAN FCGR2A Homo sapiens 2212 169 4
47 paired like homeodomain 2 PITX2_HUMAN PITX2 Homo sapiens 5308 230 4
48 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 4
49 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 PREX2_HUMAN PREX2 Homo sapiens 80243 16 4
50 myosin X MYO10_HUMAN MYO10 Homo sapiens 4651 21 4