CPRiL

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

• phosphatidylinositol 3-kinase regulatory subunit alpha
• PI3 kinase-associated p85
• PI3-kinase subunit p85-alpha
PI3K regulatory subunit alpha
growth factor receptor bound 1
phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
phosphatidylinositol 3-kinase-associated p-85 alpha
phosphoinositide-3-kinase regulatory subunit alpha
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
ptdIns-3-kinase regulatory subunit alpha
AGM7
GRB1
IMD36
p85
p85-ALPHA
p85alpha