Protein Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Organism Mus musculus
Gene ID 30955
Gene Symbol

Pik3cg

UniProt Q9JHG7 (PK3CG_MOUSE), Q3UVA4 (Q3UVA4_MOUSE), Q8C5Q7 (Q8C5Q7_MOUSE)
Relationships Total Number of functionally related compound(s) : 126
Total Number of Articles : 157
Description

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

Gene Summary

Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including G protein-coupled receptor signaling pathway; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of Rac protein signal transduction. Acts upstream of or within several processes, including cellular response to cAMP; negative regulation of fibroblast apoptotic process; and protein phosphorylation. Predicted to be located in cytosol and membrane. Predicted to be part of phosphatidylinositol 3-kinase complex, class IA and phosphatidylinositol 3-kinase complex, class IB. Predicted to be active in cytoplasm and plasma membrane. Is expressed in future spinal cord; hemolymphoid system; and thymus primordium. Human ortholog(s) of this gene implicated in autistic disorder; immunodeficiency 97; and swine influenza. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • PI3-kinase subunit gamma
  • phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
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Properties