phosphatidylinositol 3,4,5-triphosphate

thymoma viral proto-oncogene 1 ; Mus musculus







23 Article(s)
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1 32086008 CircRNA_0001449 disturbs phosphatidylinositol homeostasis and AKT activity by enhancing Osbpl5 translation in transient cerebral ischemia. 2020 Jul 1
2 33276499 PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer. 2020 Dec 2 2
3 30576423 FUNDC2 regulates platelet activation through AKT/GSK-3β/cGMP axis. 2019 Sep 1 1
4 30692625 AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. 2019 Feb 3
5 28250113 CXCL12-induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophages. 2017 Mar 1
6 28650469 A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma. 2017 Oct 26 1
7 29035165 Development of highly sensitive cell-based AKT kinase ELISA for monitoring PI3K beta activity and compound efficacy. 2017 1
8 24392697 Turning off AKT: PHLPP as a drug target. 2014 1
9 24658595 Role of aberrant PI3K pathway activation in gallbladder tumorigenesis. 2014 Feb 28 1
10 24805236 PTEN action in leukaemia dictated by the tissue microenvironment. 2014 Jun 19 1
11 25485494 Fine-tuning the intensity of the PKB/Akt signal enables diverse physiological responses. 2014 2
12 23275438 Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. 2013 Mar 6
13 23359699 Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding. 2013 Feb 12 1
14 22965143 A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability. 2012 Dec 7 4
15 21464312 Deactivation of Akt by a small molecule inhibitor targeting pleckstrin homology domain and facilitating Akt ubiquitination. 2011 Apr 19 2
16 21775285 The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. 2011 Jul 19 3
17 18339867 The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration. 2008 Mar 15 1
18 17258189 Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction. 2007 Apr 1 1
19 17720808 Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma. 2007 Sep 4 1
20 16880400 Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN. 2006 Aug 8 1
21 12900409 Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. 2003 Oct 10 1
22 11551825 Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5. 2001 Nov 1
23 10224144 FcgammaRIIb modulation of surface immunoglobulin-induced Akt activation in murine B cells. 1999 May 7 3