| Protein Name | phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 57580 |
| Gene Symbol | PREX1 |
| UniProt | Q8TCU6 (PREX1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
52
Total Number of Articles : 49 |
Description |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 |
| Gene Summary |
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008] |
| synonyms |
|
| Properties | |