Sphingolipids


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1100 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 sphingosine-1-phosphate receptor 1 S1PR1_MOUSE S1pr1 Mus musculus 13609 371 110
2 sphingosine kinase 1 SPHK1_HUMAN SPHK1 Homo sapiens 8877 366 90
3 insulin INS_HUMAN INS Homo sapiens 3630 7950 70
4 alanine--glyoxylate and serine--pyruvate aminotransferase SPYA_HUMAN AGXT Homo sapiens 189 302 43
5 sphingomyelin phosphodiesterase 1 ASM_HUMAN SMPD1 Homo sapiens 6609 259 40
6 sphingosine kinase 2 SPHK2_HUMAN SPHK2 Homo sapiens 56848 153 27
7 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 27
8 sphingosine-1-phosphate lyase 1 SGPL1_HUMAN SGPL1 Homo sapiens 8879 209 21
9 N-acylsphingosine amidohydrolase 1 ASAH1_HUMAN ASAH1 Homo sapiens 427 194 21
10 serine palmitoyltransferase long chain base subunit 1 SPTC1_HUMAN SPTLC1 Homo sapiens 10558 46 20
11 serine/threonine protein kinase YPK1 YPK1_YEAST YPK1 Saccharomyces cerevisiae S288C 853733 33 19
12 sphingosine-1-phosphate receptor 1 S1PR1_HUMAN S1PR1 Homo sapiens 1901 199 18
13 ORMDL sphingolipid biosynthesis regulator 3 ORML3_HUMAN ORMDL3 Homo sapiens 94103 34 18
14 prosaposin SAP_HUMAN PSAP Homo sapiens 5660 89 17
15 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 16
16 NPC intracellular cholesterol transporter 1 NPC1_HUMAN NPC1 Homo sapiens 4864 307 16
17 delta 4-desaturase, sphingolipid 1 DEGS1_HUMAN DEGS1 Homo sapiens 8560 116 16
18 sphingomyelin phosphodiesterase 1, acid lysosomal ASM_MOUSE Smpd1 Mus musculus 20597 156 16
19 UDP-glucose ceramide glucosyltransferase CEGT_HUMAN UGCG Homo sapiens 7357 200 15
20 inositol phosphorylceramide synthase AUR1_YEAST AUR1 Saccharomyces cerevisiae S288C 853866 20 14
21 sphingolipid homeostasis protein ORM2 ORM2_YEAST ORM2 Saccharomyces cerevisiae S288C 851064 8 14
22 sphingosine kinase 1 SPHK1_MOUSE Sphk1 Mus musculus 20698 151 14
23 inositolphosphotransferase IPT1_YEAST IPT1 Saccharomyces cerevisiae S288C 851644 38 13
24 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 13
25 sphingomyelin phosphodiesterase 3 NSMA2_HUMAN SMPD3 Homo sapiens 55512 77 13
26 inositol phosphosphingolipid phospholipase ISC1_YEAST ISC1 Saccharomyces cerevisiae S288C 856739 39 13
27 serine C-palmitoyltransferase LCB1 LCB1_YEAST LCB1 Saccharomyces cerevisiae S288C 855342 15 12
28 fatty acid elongase ELO3 ELO3_YEAST ELO3 Saccharomyces cerevisiae S288C 851087 30 12
29 serine palmitoyltransferase long chain base subunit 2 SPTC2_HUMAN SPTLC2 Homo sapiens 9517 25 11
30 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 11
31 galactosidase alpha AGAL_HUMAN GLA Homo sapiens 2717 457 10
32 ceramide transporter 1 CERT_HUMAN CERT1 Homo sapiens 10087 66 10
33 caveolin 1 CAV1_HUMAN CAV1 Homo sapiens 857 2406 10
34 glucosylceramidase beta GLCM_HUMAN GBA Homo sapiens 2629 311 10
35 sphingomyelin phosphodiesterase 2 NSMA_HUMAN SMPD2 Homo sapiens 6610 131 10
36 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 10
37 fatty acid 2-hydroxylase FA2H_HUMAN FA2H Homo sapiens 79152 51 10
38 long chain base2 LCB2A_ARATH LCB2 Arabidopsis thaliana 832432 8 9
39 ceramide synthase 1 CERS1_HUMAN CERS1 Homo sapiens 10715 64 9
40 CF transmembrane conductance regulator CFTR_HUMAN CFTR Homo sapiens 1080 1218 9
41 sphingosine hydroxylase SUR2_YEAST SUR2 Saccharomyces cerevisiae S288C 851891 19 9
42 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 9
43 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 9
44 ceramide synthase 2 CERS2_MOUSE Cers2 Mus musculus 76893 36 9
45 membrane bound transcription factor peptidase, site 1 MBTP1_HUMAN MBTPS1 Homo sapiens 8720 113 9
46 ankyrin 1 ANK1_HUMAN ANK1 Homo sapiens 286 140 9
47 glycolipid transfer protein GLTP_HUMAN GLTP Homo sapiens 51228 95 8
48 ceramide kinase CERK1_HUMAN CERK Homo sapiens 64781 58 8
49 ceramide synthase 6 CERS6_HUMAN CERS6 Homo sapiens 253782 41 8
50 clathrin light chain B CLCB_HUMAN CLTB Homo sapiens 1212 83 8