| 1 |
35203362 | S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes. | 2022 Feb 17 |
1 |
| 2 |
33484475 | Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. | 2021 Feb |
1 |
| 3 |
33609744 | Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells. | 2021 May |
2 |
| 4 |
33758708 | The Importance of Sphingosine Kinase in Breast Cancer: A Potential for Breast Cancer Management. | 2021 Feb 18 |
1 |
| 5 |
33919234 | Divergence of Intracellular Trafficking of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 3 in MCF-7 Breast Cancer Cells and MCF-7-Derived Stem Cell-Enriched Mammospheres. | 2021 Apr 21 |
1 |
| 6 |
34419228 | Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling. | 2021 Sep |
1 |
| 7 |
34502095 | A Dansyl-Modified Sphingosine Kinase Inhibitor DPF-543 Enhanced De Novo Ceramide Generation. | 2021 Aug 25 |
1 |
| 8 |
34530846 | Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes. | 2021 Sep 16 |
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| 9 |
31648078 | The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification. | 2020 Jan |
2 |
| 10 |
31863815 | Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target. | 2020 Mar |
2 |
| 11 |
31971297 | Regulatory role of SphK1 in TLR7/9-dependent type I interferon response and autoimmunity. | 2020 Mar |
2 |
| 12 |
32085881 | Sphingolipids as mediators of inflammation and novel therapeutic target in inflammatory bowel disease. | 2020 |
1 |
| 13 |
32385114 | Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation. | 2020 Jul 3 |
1 |
| 14 |
32521763 | A Novel Function of Sphingosine Kinase 2 in the Metabolism of Sphinga-4,14-Diene Lipids. | 2020 Jun 8 |
2 |
| 15 |
32637407 | Decoding the Role of Sphingosine-1-Phosphate in Asthma and Other Respiratory System Diseases Using Next Generation Knowledge Discovery Platforms Coupled With Luminex Multiple Analyte Profiling Technology. | 2020 |
2 |
| 16 |
32771459 | Mechanistic regulation of SPHK1 expression and translocation by EMAP II in pulmonary smooth muscle cells. | 2020 Dec |
2 |
| 17 |
33633691 | Role of Sphingosine Kinase in Type 2 Diabetes Mellitus. | 2020 |
2 |
| 18 |
30655321 | SPHK1 Is a Novel Target of Metformin in Ovarian Cancer. | 2019 Apr |
1 |
| 19 |
30885289 | Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription. | 2019 Mar |
2 |
| 20 |
31128248 | Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation. | 2019 Sep |
2 |
| 21 |
31352240 | Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy. | 2019 Oct |
2 |
| 22 |
29368980 | TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition. | 2018 |
2 |
| 23 |
29385066 | Expansion of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor Function in Normal and Cancer Cells: From Membrane Restructuring to Mediation of Estrogen Signaling and Stem Cell Programming. | 2018 Jan 31 |
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| 24 |
29643998 | Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice. | 2018 Mar 20 |
3 |
| 25 |
29695761 | Epigenetic variability in conversion to psychosis: novel findings from an innovative longitudinal methylomic analysis. | 2018 Apr 26 |
1 |
| 26 |
30005204 | Red light-emitting diode irradiation regulates oxidative stress and inflammation through SPHK1/NF-κB activation in human keratinocytes. | 2018 Sep |
2 |
| 27 |
30060814 | Targeting Sphingosine Kinases for the Treatment of Cancer. | 2018 |
1 |
| 28 |
28049734 | Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. | 2017 Feb 24 |
2 |
| 29 |
28479957 | 4-Hydroxynonenal Contributes to Angiogenesis through a Redox-Dependent Sphingolipid Pathway: Prevention by Hydralazine Derivatives. | 2017 |
2 |
| 30 |
28521610 | SPHK1 (sphingosine kinase 1) induces epithelial-mesenchymal transition by promoting the autophagy-linked lysosomal degradation of CDH1/E-cadherin in hepatoma cells. | 2017 May 4 |
2 |
| 31 |
28729416 | CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1. | 2017 Sep 15 |
2 |
| 32 |
28822281 | An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors. | 2017 Oct 20 |
2 |
| 33 |
28842426 | Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background. | 2017 Dec |
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| 34 |
25900155 | Periodontal inflammation and alveolar bone loss induced by Aggregatibacter actinomycetemcomitans is attenuated in sphingosine kinase 1-deficient mice. | 2016 Feb |
1 |
| 35 |
26426296 | A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay. | 2016 Jan-Feb |
1 |
| 36 |
26934645 | Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. | 2016 Mar 29 |
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| 37 |
27148053 | Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1. | 2016 |
2 |
| 38 |
27806293 | Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking. | 2016 Nov 1 |
2 |
| 39 |
25505239 | Sphingolipid pathway regulates innate immune responses at the fetomaternal interface during pregnancy. | 2015 Jan 23 |
2 |
| 40 |
26252351 | Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia. | 2015 |
2 |
| 41 |
26271487 | Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. | 2015 Dec |
2 |
| 42 |
23789924 | Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. | 2014 Jan |
2 |
| 43 |
24070975 | The role of sphingosine 1-phosphate in inflammation and cancer. | 2014 Jan |
1 |
| 44 |
24471412 | Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. | 2014 Jul 10 |
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| 45 |
24572701 | Sphingosine kinase 1 promotes malignant progression in colon cancer and independently predicts survival of patients with colon cancer by competing risk approach in South asian population. | 2014 Feb 27 |
2 |
| 46 |
24687256 | Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells. | 2014 |
1 |
| 47 |
25010828 | Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells. | 2014 |
1 |
| 48 |
25197261 | Sphingosine kinase 1 mediates head & neck squamous cell carcinoma invasion through sphingosine 1-phosphate receptor 1. | 2014 |
2 |
| 49 |
25310737 | The key role of sphingosine kinases in the molecular mechanism of neuronal cell survival and death in an experimental model of Parkinson's disease. | 2014 |
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| 50 |
23166225 | Sphingosine kinase 1 overexpression contributes to cetuximab resistance in human colorectal cancer models. | 2013 Jan 1 |
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