| 1 |
35013382 | The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism. | 2022 Jan 10 |
1 |
| 2 |
35560527 | Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid-induced DNA damage. | 2022 May |
1 |
| 3 |
33609744 | Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells. | 2021 May |
1 |
| 4 |
33852856 | Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress. | 2021 Apr 13 |
1 |
| 5 |
34106748 | N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism. | 2021 Aug 10 |
2 |
| 6 |
30620337 | Loss of the sphingolipid desaturase DEGS1 causes hypomyelinating leukodystrophy. | 2019 Mar 1 |
1 |
| 7 |
30620338 | DEGS1-associated aberrant sphingolipid metabolism impairs nervous system function in humans. | 2019 Mar 1 |
4 |
| 8 |
31227640 | Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway. | 2019 Sep |
1 |
| 9 |
31631013 | Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal. | 2019 Nov 7 |
1 |
| 10 |
28988346 | Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes. | 2018 Feb |
1 |
| 11 |
28379228 | From the configurational preference of dihydroceramide desaturase-1 towards Δ6-unsaturated substrates to the discovery of a new inhibitor. | 2017 Apr 13 |
2 |
| 12 |
26934645 | Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells. | 2016 Mar 29 |
1 |
| 13 |
23267130 | Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells. | 2013 Jan |
1 |
| 14 |
23547262 | Ablation of dihydroceramide desaturase 1, a therapeutic target for the treatment of metabolic diseases, simultaneously stimulates anabolic and catabolic signaling. | 2013 Jun |
1 |
| 15 |
22628619 | Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression. | 2012 Aug |
1 |
| 16 |
18711209 | The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis. | 2009 Jan |
1 |