| Protein Name | delta 4-desaturase, sphingolipid 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8560 |
| Gene Symbol | DEGS1 |
| UniProt | O15121 (DEGS1_HUMAN), A0A024R3P1 (A0A024R3P1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
116
Total Number of Articles : 104 |
Description |
delta 4-desaturase, sphingolipid 1 |
| Gene Summary |
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010] |
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