Protein Name delta 4-desaturase, sphingolipid 1
Organism Homo sapiens
Gene ID 8560
Gene Symbol


UniProt O15121 (DEGS1_HUMAN), A0A024R3P1 (A0A024R3P1_HUMAN)
Relationships Total Number of functionally related compound(s) : 116
Total Number of Articles : 104

delta 4-desaturase, sphingolipid 1

Gene Summary

This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]

  • sphingolipid delta(4)-desaturase DES1
  • cell migration-inducing gene 15 protein
  • degenerative spermatocyte homolog 1, lipid desaturase
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