Protein Name sphingosine-1-phosphate receptor 1
Organism Homo sapiens
Gene ID 1901
Gene Symbol


UniProt P21453 (S1PR1_HUMAN)
Relationships Total Number of functionally related compound(s) : 199
Total Number of Articles : 396

sphingosine-1-phosphate receptor 1

Gene Summary

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

  • sphingosine 1-phosphate receptor 1
  • S1P receptor 1
  • S1P receptor Edg-1
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