| Protein Name | sphingosine-1-phosphate receptor 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1901 |
| Gene Symbol | S1PR1 |
| UniProt | P21453 (S1PR1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
199
Total Number of Articles : 396 |
Description |
sphingosine-1-phosphate receptor 1 |
| Gene Summary |
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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