Sphingolipids

sphingosine kinase 2 ; Homo sapiens







27 Article(s)
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1 34826777 Resensitising proteasome inhibitor-resistant myeloma with sphingosine kinase 2 inhibition. 2022 Jan 3
2 35163559 To Be or Not to Be: The Divergent Action and Metabolism of Sphingosine-1 Phosphate in Pancreatic Beta-Cells in Response to Cytokines and Fatty Acids. 2022 Jan 31 2
3 34419228 Metabolomics and integrated network pharmacology analysis reveal Tricin as the active anti-cancer component of Weijing decoction by suppression of PRKCA and sphingolipid signaling. 2021 Sep 1
4 31648078 The role of sphingosine 1-phosphate metabolism in bone and joint pathologies and ectopic calcification. 2020 Jan 1
5 31863815 Sphingosine kinase and sphingosine-1-phosphate receptor signaling pathway in inflammatory gastrointestinal disease and cancers: A novel therapeutic target. 2020 Mar 1
6 32085881 Sphingolipids as mediators of inflammation and novel therapeutic target in inflammatory bowel disease. 2020 1
7 32637407 Decoding the Role of Sphingosine-1-Phosphate in Asthma and Other Respiratory System Diseases Using Next Generation Knowledge Discovery Platforms Coupled With Luminex Multiple Analyte Profiling Technology. 2020 1
8 30949409 Targeting sphingosine kinase 2 suppresses cell growth and synergizes with BCL2/BCL-XL inhibitors through NOXA-mediated MCL1 degradation in cholangiocarcinoma. 2019 2
9 28950390 Sphingosine kinase-2 Inhibitor ABC294640 Enhances Doxorubicin-Induced Apoptosis of NSCLC Cells via Altering Survivin Expression. 2018 Jan 2
10 29277894 The sphingosine kinase 2 inhibitor ABC294640 displays anti-non-small cell lung cancer activities in vitro and in vivo. 2018 May 15 2
11 29671030 Abnormal islet sphingolipid metabolism in type 1 diabetes. 2018 Jul 1
12 30060814 Targeting Sphingosine Kinases for the Treatment of Cancer. 2018 1
13 28939554 ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus-Infected Cell Autophagic Death and Represses Tumor Growth. 2017 Dec 2
14 29130028 Sphingosine Kinases/Sphingosine 1-Phosphate Signaling in Hepatic Lipid Metabolism. 2017 Aug 1
15 26054751 ABC294640, a sphingosine kinase 2 inhibitor, enhances the antitumor effects of TRAIL in non-small cell lung cancer. 2015 2
16 26252351 Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia. 2015 1
17 26271487 Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. 2015 Dec 1
18 25010828 Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells. 2014 1
19 23563649 Sphingosine kinase/sphingosine 1-phosphate signaling in cancer therapeutics and drug resistance. 2013 1
20 21896638 Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migration. 2011 Nov 1
21 21906625 Development of small-molecule inhibitors of sphingosine-1-phosphate signaling. 2011 Dec 1
22 20110355 Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2. 2010 Apr 2 1
23 18485923 Regulation and functions of sphingosine kinases in the brain. 2008 Sep 1
24 18511810 A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia. 2008 Aug 15 1
25 17400555 Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues. 2007 May 25 1
26 17974990 Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin. 2007 Nov 1 1
27 16118219 SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. 2005 Nov 4 2