Protein Name inositol phosphosphingolipid phospholipase
Organism Saccharomyces cerevisiae S288C
Gene ID 856739
Gene Symbol

ISC1

UniProt P40015 (ISC1_YEAST)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 32
Description

inositol phosphosphingolipid phospholipase

Gene Summary

Enables inositol phosphosphingolipid phospholipase activity. Involved in regulation of mitotic cell cycle spindle assembly checkpoint; response to salt stress; and sphingolipid metabolic process. Located in endoplasmic reticulum and mitochondrion. Is integral component of mitochondrial outer membrane. Orthologous to human SMPD2 (sphingomyelin phosphodiesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • inositol phosphosphingolipid phospholipase
  • YER019W
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Properties