Sphingolipids

sphingomyelin phosphodiesterase 1 ; Homo sapiens







40 Article(s)
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Pub. Year
#Total Relationships
1 35294847 Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1. 2022 May 1 3
2 34071826 mRNA Expression of SMPD1 Encoding Acid Sphingomyelinase Decreases upon Antidepressant Treatment. 2021 May 27 1
3 34638539 Severity of COVID-19 Patients Predicted by Serum Sphingolipids Signature. 2021 Sep 22 1
4 32203096 Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinase. 2020 Mar 2
5 31200571 Secretory Acid Sphingomyelinase in the Serum of Medicated Patients Predicts the Prospective Course of Depression. 2019 Jun 13 1
6 31778304 The Acid Sphingomyelinase/ Ceramide System as Target for Ischemic Stroke Therapies. 2019 1
7 31801274 Decreased Activity of Blood Acid Sphingomyelinase in the Course of Multiple Myeloma. 2019 Nov 30 4
8 29282302 Acid sphingomyelinase promotes mitochondrial dysfunction due to glutamate-induced regulated necrosis. 2018 Feb 2
9 29378782 Inhibition of acid sphingomyelinase disrupts LYNUS signaling and triggers autophagy. 2018 Apr 1
10 29724781 Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5. 2018 Jul 1
11 29908122 Sphingolipids in inflammatory hypoxia. 2018 Sep 25 2
12 29924727 The role of acid sphingomyelinase and modulation of sphingolipid metabolism in bacterial infection. 2018 Sep 25 2
13 28749465 Acid sphingomyelinase mediates human CD4+ T-cell signaling: potential roles in T-cell responses and diseases. 2017 Jul 27 1
14 26676316 Role of Acid Sphingomyelinase in Shifting the Balance Between Proinflammatory and Reparative Bone Marrow Cells in Diabetic Retinopathy. 2016 Apr 2
15 25597763 Changes in the metabolism of sphingolipids after subarachnoid hemorrhage. 2015 May 1
16 25666706 The emerging role of acid sphingomyelinase in autophagy. 2015 May 2
17 25762726 Nrf2 up-regulates the induction of acidic sphingomyelinase by electrophiles. 2015 Aug 1
18 25803076 Secretory sphingomyelinase in health and disease. 2015 Jun 2
19 25938590 Sphingolipid metabolism correlates with cerebrospinal fluid Beta amyloid levels in Alzheimer's disease. 2015 1
20 26528430 Association between CLN3 (Neuronal Ceroid Lipofuscinosis, CLN3 Type) Gene Expression and Clinical Characteristics of Breast Cancer Patients. 2015 1
21 24317198 Acid sphingomyelinase determines melanoma progression and metastatic behaviour via the microphtalmia-associated transcription factor signalling pathway. 2014 Apr 2
22 24951586 Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway. 2014 Aug 8 3
23 24970218 Re-configuration of sphingolipid metabolism by oncogenic transformation. 2014 Mar 14 2
24 24977483 The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy. 2014 1
25 23290778 Use of acid sphingomyelinase for cancer therapy. 2013 3
26 23658784 Characterization of acid sphingomyelinase activity in human cerebrospinal fluid. 2013 2
27 24029234 Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. 2013 Sep 9 1
28 22537678 3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate. 2012 May 15 1
29 22771321 Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis. 2012 Sep 2
30 21595704 Activity of secretory sphingomyelinase is increased in plasma of alcohol-dependent patients. 2011 Oct 2
31 20071681 Inhibition of cytokine signaling in human retinal endothelial cells through downregulation of sphingomyelinases by docosahexaenoic acid. 2010 Jun 2
32 20540705 The acid sphingomyelinase/ceramide pathway: biomedical significance and mechanisms of regulation. 2010 Jul 2
33 20956541 Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. 2010 Dec 17 2
34 19385042 Roles and regulation of secretory and lysosomal acid sphingomyelinase. 2009 Jun 1
35 17381401 Acid sphingomyelinase is required for lipid Raft TLR4 complex formation. 2007 Feb 1
36 14557812 Raft ceramide in molecular medicine. 2003 Oct 13 1
37 11751974 Ceramide-rich membrane rafts mediate CD40 clustering. 2002 Jan 1 1
38 11279185 CD95 signaling via ceramide-rich membrane rafts. 2001 Jun 8 1
39 11308026 Stimulation of acid sphingomyelinase activity by lysosomal lipids and sphingolipid activator proteins. 2001 Feb 1
40 11128869 Distribution of acid sphingomyelinase in human various body fluids. 2000 Sep 1