taxane


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459 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 139
2 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 48
3 tubulin beta 3 class III TBB3_HUMAN TUBB3 Homo sapiens 10381 231 38
4 androgen receptor ANDR_HUMAN AR Homo sapiens 367 1832 27
5 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 26
6 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 23
7 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 17
8 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 17
9 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 14
10 kallikrein related peptidase 3 KLK3_HUMAN KLK3 Homo sapiens 354 1236 11
11 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 10
12 aurora kinase A AURKA_HUMAN AURKA Homo sapiens 6790 433 9
13 proteasome 26S subunit, non-ATPase 1 PSMD1_HUMAN PSMD1 Homo sapiens 5707 302 9
14 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 9
15 immunoglobulin heavy diversity 1-7 - IGHD1-7 Homo sapiens 28509 156 8
16 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 7
17 microtubule associated protein tau TAU_HUMAN MAPT Homo sapiens 4137 1276 6
18 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
19 TLE family member 3, transcriptional corepressor TLE3_HUMAN TLE3 Homo sapiens 7090 27 6
20 folate hydrolase 1 FOLH1_HUMAN FOLH1 Homo sapiens 2346 907 6
21 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 6
22 homeobox C10 HXC10_HUMAN HOXC10 Homo sapiens 3226 819 6
23 complement C7 CO7_HUMAN C7 Homo sapiens 730 362 5
24 solute carrier family 13 member 5 S13A5_HUMAN SLC13A5 Homo sapiens 284111 79 5
25 checkpoint with forkhead and ring finger domains CHFR_HUMAN CHFR Homo sapiens 55743 27 5
26 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
27 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 5
28 forkhead box M1 FOXM1_HUMAN FOXM1 Homo sapiens 2305 352 5
29 nuclear receptor subfamily 4 group A member 1 NR4A1_HUMAN NR4A1 Homo sapiens 3164 657 5
30 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 5
31 heat shock protein family A (Hsp70) member 5 BIP_HUMAN HSPA5 Homo sapiens 3309 965 5
32 homeobox C13 HXC13_HUMAN HOXC13 Homo sapiens 3229 481 5
33 cytochrome P450 family 1 subfamily B member 1 CP1B1_HUMAN CYP1B1 Homo sapiens 1545 769 5
34 DM1 protein kinase DMPK_HUMAN DMPK Homo sapiens 1760 195 5
35 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 4
36 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 4
37 Y-box binding protein 1 YBOX1_HUMAN YBX1 Homo sapiens 4904 211 4
38 protein tyrosine kinase 2 FAK1_HUMAN PTK2 Homo sapiens 5747 1151 4
39 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 4
40 stathmin 1 STMN1_HUMAN STMN1 Homo sapiens 3925 196 4
41 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 4
42 colony stimulating factor 3 CSF3_HUMAN CSF3 Homo sapiens 1440 955 4
43 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 4
44 thrombospondin 1 TSP1_HUMAN THBS1 Homo sapiens 7057 573 3
45 O-6-methylguanine-DNA methyltransferase MGMT_HUMAN MGMT Homo sapiens 4255 549 3
46 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 3
47 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 3
48 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 3
49 glutathione S-transferase pi 1 GSTP1_HUMAN GSTP1 Homo sapiens 2950 703 3
50 cytochrome P450 family 3 subfamily A member 5 CP3A5_HUMAN CYP3A5 Homo sapiens 1577 539 3