| Protein Name | microtubule associated protein tau |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4137 |
| Gene Symbol | MAPT |
| UniProt | P10636 (TAU_HUMAN), A0A024RA19 (A0A024RA19_HUMAN), A0A024R9Y0 (A0A024R9Y0_HUMAN), A0A024R9Y1 (A0A024R9Y1_HUMAN), A0A024RA17 (A0A024RA17_HUMAN), B3KTM0 (B3KTM0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
1276
Total Number of Articles : 2294 |
Description |
microtubule associated protein tau |
| Gene Summary |
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] |
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| Properties | |