| Protein Name | checkpoint with forkhead and ring finger domains |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 55743 |
| Gene Symbol | CHFR |
| UniProt | Q96EP1 (CHFR_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
27
Total Number of Articles : 53 |
Description |
checkpoint with forkhead and ring finger domains |
| Gene Summary |
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014] |
| synonyms |
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| Properties | |