Protein Name thrombospondin 1
Organism Homo sapiens
Gene ID 7057
Gene Symbol

THBS1

UniProt P07996 (TSP1_HUMAN)
Relationships Total Number of functionally related compound(s) : 573
Total Number of Articles : 771
Description

thrombospondin 1

Gene Summary

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]

synonyms
  • thrombospondin-1
  • glycoprotein G
  • thrombospondin-1p180
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Properties