ddr


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75 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 8
2 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 6
3 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 6
4 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 5
5 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 3
6 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 3
7 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 3
8 tumor protein p53 binding protein 1 TP53B_HUMAN TP53BP1 Homo sapiens 7158 156 2
9 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein NAC8_ARATH SOG1 Arabidopsis thaliana 839145 21 2
10 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 2
11 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
12 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 2
13 speckle type BTB/POZ protein SPOP_HUMAN SPOP Homo sapiens 8405 40 2
14 ring finger protein 168 RN168_HUMAN RNF168 Homo sapiens 165918 26 2
15 eukaryotic translation initiation factor 2 alpha kinase 2 E2AK2_HUMAN EIF2AK2 Homo sapiens 5610 296 1
16 H2A clustered histone 18 H2A2A_HUMAN H2AC18 Homo sapiens 8337 96 1
17 ras homolog family member A RHOA_HUMAN RHOA Homo sapiens 387 835 1
18 QacA - qacA Staphylococcus aureus 9487077 37 1
19 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 1
20 BRCA1 associated protein 1 BAP1_HUMAN BAP1 Homo sapiens 8314 87 1
21 BP1 - BP1 Homo sapiens 474256 152 1
22 Rac family small GTPase 1 RAC1_RAT Rac1 Rattus norvegicus 363875 259 1
23 ring finger protein 2 RING2_HUMAN RNF2 Homo sapiens 6045 92 1
24 coiled-coil domain containing 6 CCDC6_HUMAN CCDC6 Homo sapiens 8030 98 1
25 forkhead box M1 Q6P1H7_MOUSE Foxm1 Mus musculus 14235 93 1
26 membrane associated ring-CH-type finger 8 MARH8_HUMAN MARCHF8 Homo sapiens 220972 373 1
27 nibrin NBN_MOUSE Nbn Mus musculus 27354 15 1
28 ataxia telangiectasia mutated ATM_MOUSE Atm Mus musculus 11920 222 1
29 FUS RNA binding protein FUS_HUMAN FUS Homo sapiens 2521 265 1
30 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 1
31 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 1
32 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 1
33 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 1
34 calcium/calmodulin-dependent protein kinase II, beta KCC2B_MOUSE Camk2b Mus musculus 12323 151 1
35 protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D_HUMAN PPM1D Homo sapiens 8493 77 1
36 sirtuin 6 SIR6_HUMAN SIRT6 Homo sapiens 51548 225 1
37 POU domain, class 5, transcription factor 1 PO5F1_MOUSE Pou5f1 Mus musculus 18999 114 1
38 microRNA 191 - MIR191 Homo sapiens 406966 31 1
39 CD274 molecule A0A4X1W783_PIG CD274 Sus scrofa 574058 125 1
40 mitogen-activated protein kinase 1 E2R2N2_CANLF MAPK1 Canis lupus familiaris 477575 65 1
41 cellular communication network factor 2 CCN2_MOUSE Ccn2 Mus musculus 14219 258 1
42 microRNA 215 - MIR215 Homo sapiens 406997 75 1
43 CREB regulated transcription coactivator 1 CRTC1_HUMAN CRTC1 Homo sapiens 23373 120 1
44 WEE1 G2 checkpoint kinase WEE1_HUMAN WEE1 Homo sapiens 7465 177 1
45 BMI1 proto-oncogene, polycomb ring finger BMI1_HUMAN BMI1 Homo sapiens 648 209 1
46 MRE11 homolog, double strand break repair nuclease MRE11_HUMAN MRE11 Homo sapiens 4361 104 1
47 egl-9 family hypoxia inducible factor 3 EGLN3_HUMAN EGLN3 Homo sapiens 112399 63 1
48 growth arrest and DNA-damage-inducible 45 alpha GA45A_MOUSE Gadd45a Mus musculus 13197 87 1
49 interferon gamma inducible protein 16 IF16_HUMAN IFI16 Homo sapiens 3428 60 1
50 histone deacetylase 6 HDAC6_MOUSE Hdac6 Mus musculus 15185 144 1