Protein Name FUS RNA binding protein
Organism Homo sapiens
Gene ID 2521
Gene Symbol


UniProt P35637 (FUS_HUMAN), Q6IBQ5 (Q6IBQ5_HUMAN), Q13344 (Q13344_HUMAN)
Relationships Total Number of functionally related compound(s) : 265
Total Number of Articles : 303

FUS RNA binding protein

Gene Summary

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

  • RNA-binding protein FUS
  • 75 kDa DNA-pairing protein
  • fus-like protein
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