CPRiL

Protein Name	FUS RNA binding protein
Organism	Homo sapiens
Gene ID	2521
Gene Symbol	FUS
UniProt	P35637 (FUS_HUMAN), Q6IBQ5 (Q6IBQ5_HUMAN), Q13344 (Q13344_HUMAN)
Relationships	Total Number of functionally related compound(s) : 265 Total Number of Articles : 303
Description	FUS RNA binding protein
Gene Summary	This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
synonyms	RNA-binding protein FUS 75 kDa DNA-pairing protein fus-like protein fused in sarcoma fusion gene in myxoid liposarcoma heterogeneous nuclear ribonucleoprotein P2 oncogene FUS oncogene TLS translocated in liposarcoma protein ALS6 ETM4 FUS1 HNRNPP2 POMP75 TLS altFUS Click to show/hide the synonyms
Properties