CPRiL

Protein Name	membrane associated ring-CH-type finger 8
Organism	Homo sapiens
Gene ID	220972
Gene Symbol	MARCHF8
UniProt	Q5T0T0 (MARH8_HUMAN), A0A024R7U2 (A0A024R7U2_HUMAN)
Relationships	Total Number of functionally related compound(s) : 373 Total Number of Articles : 447
Description	membrane associated ring-CH-type finger 8
Gene Summary	MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
synonyms	E3 ubiquitin-protein ligase MARCHF8 E3 ubiquitin-protein ligase MARCH8 RING finger protein 178 RING-type E3 ubiquitin transferase MARCH8 RING-type E3 ubiquitin transferase MARCHF8 c-mir, cellular modulator of immune recognition cellular modulator of immune recognition (c-MIR) membrane associated ring finger 8 membrane-associated RING finger protein 8 membrane-associated RING-CH protein VIII membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase CMIR MARCH-VIII MARCH8 MIR RNF178 c-MIR Click to show/hide the synonyms
Properties