Sterols


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1069 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 3-hydroxy-3-methylglutaryl-CoA reductase HMDH_HUMAN HMGCR Homo sapiens 3156 571 87
2 low density lipoprotein receptor LDLR_HUMAN LDLR Homo sapiens 3949 826 84
3 ATP binding cassette subfamily G member 5 ABCG5_HUMAN ABCG5 Homo sapiens 64240 66 61
4 ATP binding cassette subfamily G member 8 ABCG8_HUMAN ABCG8 Homo sapiens 64241 48 52
5 NPC intracellular cholesterol transporter 1 NPC1_HUMAN NPC1 Homo sapiens 4864 307 52
6 SREBF chaperone SCAP_HUMAN SCAP Homo sapiens 22937 118 43
7 sterol regulatory element binding transcription factor 2 SRBP2_HUMAN SREBF2 Homo sapiens 6721 209 42
8 cytochrome P450 family 51 subfamily A member 1 CP51A_HUMAN CYP51A1 Homo sapiens 1595 167 37
9 sterol regulatory element binding transcription factor 1 SRBP1_HUMAN SREBF1 Homo sapiens 6720 451 37
10 ATP binding cassette subfamily G member 5 ABCG5_MOUSE Abcg5 Mus musculus 27409 58 35
11 nuclear receptor subfamily 1, group H, member 3 NR1H3_MOUSE Nr1h3 Mus musculus 22259 362 33
12 NPC1 like intracellular cholesterol transporter 1 NPCL1_HUMAN NPC1L1 Homo sapiens 29881 109 29
13 oxysterol binding protein OSBP1_HUMAN OSBP Homo sapiens 5007 65 29
14 insulin induced gene 1 INSI1_HUMAN INSIG1 Homo sapiens 3638 54 28
15 ATP binding cassette subfamily G member 8 ABCG8_MOUSE Abcg8 Mus musculus 67470 48 27
16 ATP binding cassette subfamily A member 1 ABCA1_HUMAN ABCA1 Homo sapiens 19 574 23
17 insulin INS_HUMAN INS Homo sapiens 3630 7950 22
18 apolipoprotein E APOE_HUMAN APOE Homo sapiens 348 1088 22
19 sterol carrier protein 2 SCP2_HUMAN SCP2 Homo sapiens 6342 142 21
20 Upc2p UPC2_YEAST UPC2 Saccharomyces cerevisiae S288C 851799 24 21
21 CCHC-type zinc finger nucleic acid binding protein CNBP_HUMAN CNBP Homo sapiens 7555 138 21
22 component of oligomeric golgi complex 2 COG2_HUMAN COG2 Homo sapiens 22796 427 20
23 farnesyl-diphosphate farnesyltransferase 1 FDFT_HUMAN FDFT1 Homo sapiens 2222 151 20
24 ATP binding cassette subfamily G member 1 ABCG1_HUMAN ABCG1 Homo sapiens 9619 193 19
25 cytochrome P450 family 27 subfamily A member 1 CP27A_HUMAN CYP27A1 Homo sapiens 1593 433 19
26 sterol 14-demethylase CP51_YEAST ERG11 Saccharomyces cerevisiae S288C 856398 57 18
27 C-5 sterol desaturase ERG3_YEAST ERG3 Saccharomyces cerevisiae S288C 850745 43 18
28 steroidogenic acute regulatory protein STAR_HUMAN STAR Homo sapiens 6770 429 18
29 3-hydroxy-3-methylglutaryl-Coenzyme A reductase HMDH_MOUSE Hmgcr Mus musculus 15357 170 17
30 ATP binding cassette subfamily G member 1 ABCG1_MOUSE Abcg1 Mus musculus 11307 112 17
31 sterol 24-C-methyltransferase ERG6_YEAST ERG6 Saccharomyces cerevisiae S288C 855003 66 17
32 3-hydroxy-3-methylglutaryl-CoA reductase HMDH_RAT Hmgcr Rattus norvegicus 25675 353 17
33 insulin induced gene 2 INSI2_HUMAN INSIG2 Homo sapiens 51141 36 16
34 ATP-binding cassette, sub-family A (ABC1), member 1 ABCA1_MOUSE Abca1 Mus musculus 11303 321 16
35 apolipoprotein A1 APOA1_HUMAN APOA1 Homo sapiens 335 1112 15
36 NPC intracellular cholesterol transporter 2 NPC2_HUMAN NPC2 Homo sapiens 10577 99 15
37 sterol regulatory element binding transcription factor 1 SRBP1_MOUSE Srebf1 Mus musculus 20787 409 14
38 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 14
39 oxysterol-binding protein KES1 KES1_YEAST KES1 Saccharomyces cerevisiae S288C 855958 29 13
40 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMDH_CRIGR Hmgcr Cricetulus griseus 100756363 41 13
41 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 12
42 nuclear receptor subfamily 1 group H member 4 NR1H4_HUMAN NR1H4 Homo sapiens 9971 443 12
43 farnesyl diphosphate synthase FPPS_HUMAN FDPS Homo sapiens 2224 223 12
44 sterol regulatory element binding factor 2 SRBP2_MOUSE Srebf2 Mus musculus 20788 132 12
45 squalene epoxidase ERG1_HUMAN SQLE Homo sapiens 6713 248 12
46 ATP-binding cassette sterol transporter AUS1 AUS1_YEAST AUS1 Saccharomyces cerevisiae S288C 854175 11 12
47 24-dehydrocholesterol reductase DHC24_HUMAN DHCR24 Homo sapiens 1718 134 11
48 high mobility group AT-hook 1 HMGA1_HUMAN HMGA1 Homo sapiens 3159 170 11
49 StAR related lipid transfer domain containing 4 STAR4_HUMAN STARD4 Homo sapiens 134429 15 11
50 Sut1p SUT1_YEAST SUT1 Saccharomyces cerevisiae S288C 852714 19 10